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Pennsylvania vs Drexel Prediction 11/21/2025 Today’s College Basketball Picks

Drexel Dragons guard Jamie Bergens (3) dribbles against the Delaware Fightin' Blue Hens guard Christian Ray (5) during critical late-season CAA basketball game at the Bob Carpenter Center in Newark, Monday, Feb. 26, 2024. Drexel won 70-60.

Drexel Dragons guard Jamie Bergens (3) dribbles against the Delaware Fightin' Blue Hens guard Christian Ray (5) during critical late-season CAA basketball game at the Bob Carpenter Center in Newark, Monday, Feb. 26, 2024. Drexel won 70-60.

MATCHUP Pennsylvania Quakers Drexel Dragons
Team Records 2-2 2-3
Spread +5.5 -110 -5.5 -110
Moneyline +185 -225
Total Over 153.5 (-112) Under 153.5 (-108)
Where Daskalakis Athletic Center, Philadelphia, PA
When Friday, November 21, 2025
Time 07:00 PM EST
TV FloSports
In this article, we will formulate a Penn vs Drexel Prediction for this College Basketball game on Friday, November 21st. Let’s take a look at the prediction for this College Basketball matchup.

Drexel Dragons Preview


Drexel has a 2-3 record this season and are tied for 11th place in the CAA conference. They are 1-3 ATS, 2-2 in Over/Under and have a 2-0 home record and a 0-2 away record. Drexel is coming off a 75-43 home win against NJIT and will face Old Dominion, Morgan State and American next.

Offensively, Drexel averages 73.2 points per game, which ranks 276th in the nation, while defensively, they allow 69.6 points per game (119th). The Dragons shoot with 41.0% from the field (321st), and with 32.3% from beyond the arc (228th). They shoot with 58.9% from the free throw line (360th), and grab 42.8 rebounds per game (16th), while dishing out 16.2 assists per game (132nd) and committing 13.6 turnovers per game (248th).

Shane Blakeney leads Drexel in scoring, with an average of 12.6 points and 6 rebounds. Eli Beard follows with 11.8 points and 2 assists per game, while Kevon Vanderhorst adds 10.8 points and 4 rebounds and 3 assists per game.

Penn Quakers Preview


Penn has a 2-2 record this season and are tied for 5th place in the Ivy conference. They are 1-2 ATS, 2-1 in Over/Under and have a 2-0 home record and a 0-2 away record. Penn is coming off a 83-74 home win against Saint Joseph’s and will face Merrimack, La Salle and Hofstra next.

Offensively, Penn averages 90.3 points per game, which ranks 54th in the nation, while defensively, they allow 84.0 points per game (332nd). The Quakers shoot with 44.7% from the field (217th), and with 41.6% from beyond the arc (20th). They shoot with 75.0% from the free throw line (86th), and grab 41.3 rebounds per game (94th), while dishing out 14.8 assists per game (192nd) and committing 14.0 turnovers per game (264th).

Ethan Roberts leads Penn in scoring, with an average of 23.3 points and 8 rebounds. Michael Zanoni follows with 13.5 points per game, while TJ Power adds 13.5 points and 9 rebounds per game.

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Penn vs Drexel Prediction


In this Penn vs Drexel Prediction, Drexel is coming as -5.5 home favorites. Both teams have almost identical overall records, but Drexel has been undefeated at home, while Penn has been winless on the road. Drexel has a superior defense, allowing 14.4 points per game less than Penn and also are the 16th-best rebounding team in the country and are better in assists made, so I expect them to get the job done at home today. Take Drexel and lay the points.

Nikos Lagouretos's Pick: Drexel -5.5

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