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Loyola Chicago vs St. Joseph’s Prediction 2/21/2026 Today’s College Basketball Picks

Dec 11, 2025; Syracuse, New York, USA; Saint Joseph's Hawks guard Deuce Jones (2) attempts a dunk as Syracuse Orange forward William Kyle III (42) and forward Tyler Betsey (5) defend during the second half at the JMA Wireless Dome. Mandatory Credit: Rich Barnes-Imagn Images

Dec 11, 2025; Syracuse, New York, USA; Saint Joseph's Hawks guard Deuce Jones (2) attempts a dunk as Syracuse Orange forward William Kyle III (42) and forward Tyler Betsey (5) defend during the second half at the JMA Wireless Dome. Mandatory Credit: Rich Barnes-Imagn Images

MATCHUP Loyola Chicago Ramblers St. Joseph's Hawks
Team Records 6-21 16-10
Spread +9.5 -105 -9.5 -115
Moneyline +425 -575
Total Over 143.5 (-110) Under 143.5 (-110)
Where Michael J. Hagan '85 Arena, Philadelphia, PA
When Saturday, February 21, 2026
Time 12:00 PM EST
TV ESPNU

The Loyola-Chicago Ramblers and Saint Joseph’s Hawks meet Saturday in college basketball action at the Michael J. Hagan ’85 Arena. Here’s a Loyola Chicago vs St. Joseph’s Prediction. This article will include a Loyola Chicago vs St. Joseph’s Pick.

Loyola-Chicago Ramblers Betting Preview

The Loyola-Chicago Ramblers lost to Saint Louis and Fordham, and play Richmond next. Loyola-Chicago has lost 10 of its last 11 games.

The Loyola-Chicago Ramblers are averaging 67 points on 41.8 percent shooting and allowing 77.3 points on 44.6 percent shooting. Xavier Amos is averaging 11.1 points and 0.7 assists, while Miles Rubin is averaging 10.9 points and 7.2 rebounds. Justin Moore is the third double-digit scorer, and Kayde Dotson is grabbing 2.5 rebounds. The Loyola-Chicago Ramblers are shooting 30.7 percent from beyond the arc and 66.7 percent from the free throw line. The Loyola-Chicago Ramblers are allowing 38.4 percent shooting from deep and are grabbing 30.7 rebounds per game.

Saint Joseph’s Hawks Betting Preview

The Saint Joseph’s Hawks lost to Fordham, beat St. Bonaventure, and they play George Mason next. Saint Joseph’s has won 8 of its last 11 games.

The Saint Joseph’s Hawks are averaging 73.5 points on 42.4 percent shooting and allowing 71.2 points on 41.2 percent shooting. Deuce Jones is averaging 15.8 points and 4.3 rebounds, while Jaiden Glover-Toscano is averaging 15.4 points and 4.5 rebounds. Derek Simpson is the third double-digit scorer and Dasear Haskins is grabbing 6.3 rebounds. The Saint Joseph’s Hawks are shooting 30.4 percent from beyond the arc and 74.7 percent from the free throw line. The Saint Joseph’s Hawks are allowing 32.7 percent shooting from deep and are grabbing 36.2 rebounds per game.

Why the Saint Joseph’s Hawks will win

Total Points Facts

Loyola Chicago vs St. Joseph’s Prediction

We’ve been blindly fading Loyola Chicago all season, and it’s worked up to this point. Loyola Chicago isn’t good on either side of the ball, doesn’t win, and is 8-19 ATS on the season. St. Joseph’s beat the Ramblers on the road a month ago by 21 points. St. Joseph’s has covered 8 of its last 10 games and is looking more and more like a sleeper in the A10 tournament. Two teams heading in different directions. Loyola Chicago sucks. Give me St. Joe’s in a double-digit home victory.

Randy Chambers's Pick: St. Joseph's -9.5

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