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Lipscomb vs Iowa State Prediction 3/21/25 College Basketball Picks

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Iowa State (24-9) vs Lipscomb (25-9)

March 21, 2025 at 01:30 PM EDT

The Line: Betting Odds: Iowa State -14.5 — Over/Under: 142.5

(Get latest betting odds)

The Lipscomb Bisons and Iowa State Cyclones meet Friday in the college basketball First Round at the Fiserv Forum. Here’s a Lipscomb vs Iowa State Prediction. This article will include a Lipscomb vs Iowa State Pick.

Lipscomb Bisons Betting Preview 

The Lipscomb Bisons recently beat Central Arkansas, Austin Peay, Queens, and North Alabama. Lipscomb has won six straight games and is 11-1 overall since February 1. 

The Lipscomb Bisons are averaging 79.3 points on 47.3 percent shooting and allowing 67.3 points on 42.3 percent shooting. Jacob Ognacevic is averaging 20.1 points and 8.1 rebounds, while Will Pruitt is averaging 13.2 points and 5.9 rebounds. Gyasi Powell is the third double-digit scorer and Joe Anderson is grabbing 3.5 rebounds. The Lipscomb Bisons are shooting 35.9 percent from beyond the arc and 79.4 percent from the free throw line. The Lipscomb Bisons are allowing 30.8 percent shooting from deep and are grabbing 33.3 rebounds per game.

Iowa State Cyclones Betting Preview 

The Iowa State Cyclones recently played Arizona, BYU, Kansas State, and Cincinnati. Iowa State has seen four of its nine losses come in its last seven games.

The Iowa State Cyclones are averaging 80.4 points on 48 percent shooting and allowing 68.1 points on 41.7 percent shooting. Curtis Jones is averaging 17.1 points and 2.3 assists, while Keshon Gilbert is averaging 13.4 points and 3.5 rebounds. Joshua Jefferson is the third double-digit scorer and Tamin Lipsey is grabbing 2.6 rebounds. The Iowa State Cyclones are shooting 35.8 percent from beyond the arc and 75.7 percent from the free throw line. The Iowa State Cyclones are allowing 33.2 percent shooting from deep and are grabbing 32.7 rebounds per game.

Why the Iowa State Cyclones will win

  • Iowa State has won nine of its last 10 games against non-Conference opponents.
  • Lipscomb has lost the first half in each of its last three games played at neutral venues.

Why the Lipscomb Bisons will win

  • Lipscomb has won 15 of its last 16 day games.

Total Points Facts

  • Seven of Iowa State’s last eight day games against non-Conference opponents have produced a total of 154+ points.
  • Six of Lipscomb’s last seven games against non-Conference opponents have produced a total of 142 or fewer points.

Matchup/League Facts

  • Iowa State ranks 12th among Division 1 teams for free throws made per game this season (17.6).
  • Iowa State ranks 15th among Division 1 teams for point differential per game this season (+12.6).
  • Lipscomb ranks 5th among Division 1 teams for opponent free throw percentage this season (66.9%).
  • Lipscomb ranks 8th among Division 1 teams for free throw percentage this season (79.4%).

Lipscomb vs Iowa State Injury Report

Lipscomb is without Dylan Faulkner due to a foot injury. Keshon Gilbert is out for Iowa State, while Tamin Lipsey is questionable with a groin injury. 

Lipscomb vs Iowa State Prediction

Iowa State is one of the more balanced teams in the tournament and is capable of a deep run if it plays to its potential. The problem is Iowa State cooled off down the stretch and should have some issues defensively. Lipscomb doesn’t have the talent that’s going to scare Iowa State, but Lennie Acuff is a coach who has been successful everywhere he’s gone and has nine different Coach of the Year awards. Lipscomb is also lighting it up offensively over the last month and that includes scoring no less than 75 points in nine of its last 10 games. If Lipscomb can hit some shots early, this could get somewhat interesting. I want the points with the Bisons.  

Randy Chambers's Pick: Lipscomb +14.5

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