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Howard vs Duke Prediction 11/23/2025 Today’s College Basketball Picks

Nov 21, 2025; Durham, North Carolina, USA; Duke Blue Devils forward Cameron Boozer (12) looks to pass as Niagara Purple Eagles forward Will Shortt (32) defends during the first half at Cameron Indoor Stadium. Mandatory Credit: Rob Kinnan-Imagn Images

Nov 21, 2025; Durham, North Carolina, USA; Duke Blue Devils forward Cameron Boozer (12) looks to pass as Niagara Purple Eagles forward Will Shortt (32) defends during the first half at Cameron Indoor Stadium. Mandatory Credit: Rob Kinnan-Imagn Images

MATCHUP Howard Bison Duke Blue Devils
Team Records 3-3 6-0
Where Cameron Indoor Stadium, Durham, NC
When Sunday, November 23, 2025
Time 04:00 PM EST
TV ACC Network
In this article we will formulate a Howard vs Duke prediction for this College Basketball game on Sunday, November 23rd at Cameron Indoor Stadium in Durham, North Carolina. Let’s take a look at the prediction for this College Basketball matchup.

Howard Bison Betting Preview

The Howard Bison are 3-3 this season after they defeated Niagara by a score of 80-70 in their last game. Howard trailed 37-29 at halftime, but they scored 51 points in the second half for the win. The Bison shot 44% from the field, 29% on three pointers, and 70% on free throws in the game. Bryce Harris led Howard with 20 points and five rebounds, while Travelle Bryson added 15 points and three rebounds in the win. 

Prior to that game, Howard lost to Stetson by a score of 64-60, but did beat Alcorn State by a score of 72-64 before that. The Bison have scored 74.4 points per game with 32.6 rebounds and 15.4 assists per game, while they have allowed 72.0 points against per game this season. Bryce Harris is averaging 22.4 points and 7.8 rebounds per game, while Alex Cotton is averaging 14.3 points and 2.0 rebounds per game for the Bison. Howard is shooting 46.4% from the field, 73.3% on free throws, and 39.2% on three pointers this season. 

Duke Blue Devils Betting Preview

The Duke Blue Devils are 6-0 this year after they defeated Niagara by a score of 100-42 in their last game. Duke led 47-19 at halftime and added 53 points in the second half for the blowout win. The Blue Devils shot 58% from the field, 52% on three pointers, and 79% on free throws in the game. Patrick Ngongba II led Duke with 17 points and eight rebounds, while Isaiah Evans added 12 points and three assists in the win. 

Prior to that game, Duke defeated Kansas by a score of 78-66 and Indiana State by a score of 100-62. The Blue Devils have scored 93.7 points per game with 44.2 rebounds and 20.7 assists per game, while they have allowed 57.2 points against per game this season. Cameron Boozer is averaging 20.3 points and 9.5 rebounds per game, while Isaiah Evans is averaging 13.3 points and 3.3 rebounds per game for the Blue Devils. Duke is shooting 51% from the field, 74.2% on free throws, and 38.5% on three pointers this year. 

Why the Duke Blue Devils will win

Howard vs Duke Prediction 

Duke comes into this matchup with an undefeated record to start the season and they are a huge favorite to get this win at home. The Blue Devils are shooting 51% from the field this year and they have scored at least 95 points in four of their last five games. Howard is shooting 46% from the field and they scored just 60 points in their last road game against Stetson. I think the Duke defense will lock down once again in this contest and I am taking the under here.

David Racey's Pick: Under 150.5

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