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Houston vs Iowa State Prediction 2/16/2026 Today’s College Basketball Picks

Mar 20, 2024; Omaha, NE, USA;  Iowa State Cyclones cheerleaders perform during the NCAA first round practice session at CHI Health Center Omaha. Mandatory Credit: Steven Branscombe-Imagn Images

Mar 20, 2024; Omaha, NE, USA; Iowa State Cyclones cheerleaders perform during the NCAA first round practice session at CHI Health Center Omaha. Mandatory Credit: Steven Branscombe-Imagn Images

MATCHUP Houston Cougars Iowa State Cyclones
Team Records 23-2 22-3
Spread +2.5 -110 -2.5 -110
Moneyline +114 -135
Total Over 134.5 (-110) Under 134.5 (-110)
Where Hilton Coliseum, Ames, IA
When Monday, February 16, 2026
Time 09:00 PM EST
TV ESPN

The Houston Cougars and the Iowa State Cyclones meet Monday in college basketball action from Hilton Coliseum in Ames. Here’s a Houston vs Iowa State prediction. We will look at this from a betting perspective and determine the best Houston vs Iowa State pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Houston Cougars Betting Preview

Houston managed to get victories in six of their opening seven outings this year. Next came wins over Notre Dame, Florida State, Jackson State, New Orleans, Arkansas, Middle Tennessee, Cincinnati, Texas Tech, Baylor, West Virginia and Arizona State before a loss to Texas Tech. After that were more wins over TCU, Cincinnati, UCF, BYU and Utah in order for a 22-2 overall record in the books over the Cougars’ first 24 outings of the season.

In game 25 versus Kansas State back on Saturday, Houston was looking pretty on a 33-19 advantage as the game moved into the second half. The Cougars kept the pace from there on a 45-45 run and took the eventual victory on their home floor 78-64 in the end. Leading the way was Emanuel Sharp with 23 points, six rebounds and two assists in 30 minutes during the win.

Iowa State Cyclones Betting Preview

Over on the Cyclones’ side, they ran the table on a perfect 16-0 start to the season. Iowa State would then take consecutive losses to Kansas and Cincinnati before picking it back up again with wins over Central Florida, Oklahoma State, Colorado, Kansas State and Baylor. After another loss to TCU, Iowa State was sitting at 21-3 after their first 24 games of the year.

Matched up against Kansas over the weekend the Cyclones were looking good at halftime sitting on a 37-27 advantage. Iowa State hit a 37-29 run in the second half and took the eventual victory 74-56 on their home court. Leading the Cyclones was Milan Momcilovic with 18 points, three rebounds and one assist. Four different Iowa State players each added 11 points in the win.

Houston Cougars @ Iowa State Cyclones Betting Trends: February 16, 2026

Why the Iowa State Cyclones will win

Why the Houston Cougars will win

Total Points Facts

Houston vs Iowa State Prediction

I’ll lean toward Iowa State but it’ll be a fun one to watch no matter what. The Cyclones took care of a great Kansas team over the weekend, surging to a home win on 43.5 percent shooting and just six turnovers. Iowa State gave up just 37.3 percent shooting on the other side but did go just 9-of-17 (52.9 percent) at the line. The Cyclones have won six of their last seven games, scoring 72 or more points in each of those victories along the way.

As for Houston, they shot a tepid 40.7 percent from the field with 15 turnovers in the win over Kansas State last weekend. The Cougars gave up just 35.1 percent shooting on the other side and added 37 rebounds with 18 team assists, though. Houston is sitting on a six-game win streak right now, posting 76 or more points in five of those. We should have a really fun matchup here regardless of the outcome.

Andrew Jett's Pick: Iowa State Cyclones -1.5

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