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Eastern Kentucky vs Eastern Illinois Prediction 12/10/2025 Today’s College Basketball Picks

Nov 11, 2025; South Bend, Indiana, USA; Eastern Illinois Panthers guard Zion Fruster (5) shoots against the Notre Dame Fighting Irish during the first half at Purcell Pavilion at the Joyce Center. Mandatory Credit: Michael Caterina-Imagn Images

Nov 11, 2025; South Bend, Indiana, USA; Eastern Illinois Panthers guard Zion Fruster (5) shoots against the Notre Dame Fighting Irish during the first half at Purcell Pavilion at the Joyce Center. Mandatory Credit: Michael Caterina-Imagn Images

MATCHUP Eastern Kentucky Colonels Eastern Illinois Panthers
Team Records 2-7 2-6
Spread -5.5 -108 +5.5 -112
Moneyline -238 +195
Total Over 149.5 (-115) Under 149.5 (-105)
Where Groniger Arena, Charleston, IL
When Wednesday, December 10, 2025
Time 08:00 PM EST
TV ESPN+

The Eastern Kentucky Colonels and the Eastern Illinois Panthers meet Wednesday in college basketball action from the Groniger Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Eastern Kentucky Colonels vs. Eastern Illinois Panthers prediction.

Eastern Kentucky Colonels Recap

The Eastern Kentucky Colonels come into this game looking to build on their 122-67 win over subdivision IU East last time out to sit at 2-7 this season. After this game, Eastern Kentucky will head home for a game against Miami-Ohio.

Colonels Still Looking For First D-I Win

Juan Cranford Jr. leads Eastern Kentucky in scoring with 12.6 PPG along with 2.8 RPG while Austin Ball has 11.8 PPG with 5.2 RPG and Montavious Myrick has 11 PPG with a team-high 6.9 RPG to lead EKU in rebounding as well as 2.9 APG this season to round out the trio of double-digit scorers for Eastern Kentucky so far this season. Turner Buttry has 9.9 PPG with 2.1 RPG and 2.6 APG and MJ Williams has 9.7 PPG with 3.7 RPG and a team-high 3 APG to lead Eastern Kentucky in assists this season. Jalen Cooper has 9.5 PPG with 5.6 RPG and Jayden Harris has 9.3 PPG with 3.7 RPG and Tyler Jackson has 9 PPG this season. As a team, Eastern Kentucky is averaging 85.8 PPG on 43% shooting from the field, 33.1% from three and 70.6% from the foul line this season.

Eastern Illinois Panthers Recap

The Eastern Illinois Panthers come into this game looking to bounce back from their 82-74 loss at the hands of Lindenwood last time out to sit at 2-6 this season. After this game, Eastern Illinois will take on Iowa State on the road.

Panthers Lose 3 In A Row

Zion Fruster has 16.6 PPG with 3.6 RPG and 2 APG in 5 games played so far this season while Kooper Jacobi has 11.1 PPG with 5.6 RPG and a team-high 2.4 APG to lead the Panthers in assists. Terry McMorris has 10.6 PPG with a team-high 6.5 RPG to lead the Panthers in rebounding and to cap off the trio of double-digit scorers for Eastern Illinois so far this season. Preston Turner has 9.7 PPG while Meechie White has 9.5 PPG with 3.1 RPG and 2.4 APG as well this season. As a team, Eastern Illinois is averaging 62.1 PPG on 41% shooting from the field, 27.6% from three and 73.5% from the foul line this season.

Eastern Kentucky Colonels @ Eastern Illinois Panthers Betting Trends: December 10, 2025

Why the Eastern Illinois Panthers will win

Why the Eastern Kentucky Colonels will win

Total Points Facts

Matchup/League Facts

Eastern Kentucky Colonels vs. Eastern Illinois Panthers Prediction

I’m on Eastern Kentucky here. It’s hard to back an EKU team on the road laying points here, when they have yet to beat a D-I team this season. However, Eastern Illinois is also kind of in the same boat, and Eastern Kentucky is probably better than their record would indicate. I think EKU’s favored on the road for a reason. Give me the Colonels here.

Chris Ruffolo's Pick: Eastern Kentucky -5.5

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