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Dayton vs La Salle Prediction 1/21/2026 Today’s College Basketball Picks

Feb 1, 2020; Dayton, Ohio, USA; A Dayton Flyers cheerleader performs during the second half against the Fordham Rams at University of Dayton Arena. Mandatory Credit: David Kohl-Imagn Images

Feb 1, 2020; Dayton, Ohio, USA; A Dayton Flyers cheerleader performs during the second half against the Fordham Rams at University of Dayton Arena. Mandatory Credit: David Kohl-Imagn Images

MATCHUP Dayton Flyers La Salle Explorers
Team Records 14-4 6-13
Spread -10.5 -105 +10.5 -115
Moneyline -625 +455
Total Over 136.5 (-105) Under 136.5 (-115)
Where John Glaser Arena, Philadelphia, PA
When Wednesday, January 21, 2026
Time 06:30 PM EST
TV ESPN+

The Dayton Flyers and the La Salle Explorers meet Wednesday in college basketball action from Tom Gola Arena. Here’s a Dayton vs La Salle prediction. We will look at this from a betting perspective and determine the best Dayton vs La Salle pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Dayton Flyers Betting Preview

The Flyers kicked off their season with a nice 6-1 run, then lost two of the next three to BYU and Virginia. It’s been a 7-1 stretch since then featuring wins over North Florida, Florida State, Fordham, Loyola Chicago, George Washington, Duquesne and Loyola Chicago again. Over the first 18 games of the season that gives the Flyers a pretty solid 14-4 overall record in the books so far.

In the home rematch versus Loyola back on Friday the Flyers entered the second half sporting a slim one-point lead 31-30. Dayton woke up from there, hitting a nice 47-21 advantage on the way to a big win 78-51. De’Shayne Montgomery led the team with 21 points and two rebounds, while Javon Bennett added 19 points with four assists and two boards. Jaiun Simon chipped in with 14 points, six rebounds and three assists as well.

La Salle Explorers Betting Preview

Over on the La Salle side, they’ve had a rough year. The Explorers could only muster four wins over their first 10 games, then hit a losing streak versus Long Island U, High Point, Michigan, George Mason and George Washington. La Salle is 2-2 in their last four games with wins over Rhode Island and St. Bonaventure, however. That gives the Explorers a 6-13 record in their first 19 outings of the season.

Matched up against St. Bonaventure on Saturday, the Explorers were up 38-37 by the end of the first half. La Salle kept it going from there on a 40-37 run and eventually took the home victory 78-74. Jerome Brewer topped the team in scoring with 27 points, six rebounds and two assists, while Jaeden Marshall was close behind on 23 points, three rebounds and two assists. Rob Dockery added 10 points and six assists in the win.

Dayton Flyers @ La Salle Explorers Betting Trends: January 21, 2026

Why the Dayton Flyers will win

Dayton vs La Salle Prediction

I might take a stab on the Explorers here but I’ll probably just stay away. La Salle posted a nice home win over a pretty decent St. Bonaventure team in their last outing, shooting a stellar 58.1 percent from the field, 57.1 percent (8-of-14) from outside and a perfect 20-of-20 from the line. The Explorers had a 25-19 rebounding advantage but did cough up 17 turnovers along the way. La Salle is 2-2 over their last four games, and they’ve scored 72 or more points in three of those four.

As for Dayton, they started out slowly in their recent home win over Loyola but closed on a nice run. The Flyers eventually shot 44.2 percent from the field with 43.5 percent (10-of-23) from 3-point range and 78.6 percent (22-of-28) from the line. Dayton is riding a five-game win streak right now and should be in control here as well. I think La Salle has a shot at getting in there if they can keep the scoring up, though.

Andrew Jett's Pick: La Salle Explorers +10.5

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