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Clemson vs Syracuse Prediction 12/31/2025 Today’s College Basketball Picks

Clemson Tigers forward RJ Godfrey (0) drives past Cincinnati Bearcats forward Halvine Dzellat (65) Sunday, Dec. 21, 2025, during the NCAA men’s basketball game at Bon Secours Wellness Arena in Greenville, South Carolina.

Clemson Tigers forward RJ Godfrey (0) drives past Cincinnati Bearcats forward Halvine Dzellat (65) Sunday, Dec. 21, 2025, during the NCAA men’s basketball game at Bon Secours Wellness Arena in Greenville, South Carolina.

MATCHUP Clemson Tigers Syracuse Orange
Team Records 10-3 9-4
Spread +1.5 -118 -1.5 -102
Moneyline -105 -115
Total Over 141.5 (-115) Under 141.5 (-105)
Where JMA Wireless Dome, Syracuse, NY
When Wednesday, December 31, 2025
Time 02:00 PM EST
TV ESPN2
The Clemson Tigers and the Syracuse Orange meet Wednesday in college basketball action from the JMA Wireless Dome. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Clemson Tigers vs. Syracuse Orange prediction.

Clemson Tigers Recap

The Clemson Tigers come into this game looking to add on to their 68-65 win over Cincinnati last time out to sit at 10-3 this season. After this game, Clemson will head on the road for a game against Pitt.

Tigers Win 3 In A Row

RJ Godfrey leads the Tigers in scoring and rebounding with 12.1 PPG and 6.4 RPG along with 2.3 APG while Carter Welling has 10.6 PPG with 6.2 RPG this season. Jestin Porter has 10.2 PPG with 2.1 RPG to cap off the trio of double-digit scorers for Clemson so far this season. Dillon Hunter has 9.2 PPG with 3.6 RPG and 2.7 APG while Nick Davidson has 8 PPG with 4.9 RPG and Jake Wahlin has 8 PPG with 4.8 RPG as well this season. Zac Foster’s added 7.8 PPG with 2.9 RPG and 2.9 APG as well to lead the Tigers in assists so far this season. As a team, Clemson is averaging 85.1 PPG on 46.3% shooting from the field, 32.8% from three and 74.9% from the foul line this season.

Syracuse Orange Recap

The Syracuse Orange come into this game looking to add on to their 77-48 win over Stonehill last time out to sit at 9-4 this season. After this game, Syracuse will head on the road for a game against Georgia Tech.

Orange Win 3 Straight

Donnie Freeman leads the Orange in scoring with 17.5 PPG along with 5.3 RPG and 2.5 APG while Kiyan Anthony has 10.9 PPG with 2.2 RPG and William Kyle III has a team-high 8.2 RPG to lead the Orange in rebounding this season. J.J. Starling has 10.6 PPG with 3 RPG and 2.4 APG to cap off the group of double-digit scorers for Syracuse so far this season while Nate Kingz has 9.7 PPG with 4.4 RPG and Tyler Betsey has 8.3 PPG with 2.9 APG and Naithan George has 8.3 PPG with 2.9 RPG and a team-high 5 APG to lead Syracuse in assists so far this season. As a team, Syracuse is averaging 72.9 PPG on 46.3% shooting from the field, 30% from three and 58% from the foul line this season.

Clemson Tigers @ Syracuse Orange Betting Trends: December 31, 2025


Why the Syracuse Orange will win

Why the Clemson Tigers will win

Total Points Facts

Matchup/League Facts

Clemson Tigers vs. Syracuse Orange Prediction

I’m on Clemson here. I think this is going to be a low-scoring rock fight, but the thing is in this game that Syracuse is the worst free throw shooting team in the country and if this is going to be a tight game as this total kind of indicates that it will be, the Tigers’ clear edge and disparity at the free throw line is going to be a massive edge late. I’ll roll with Clemson for the road win and cover here.

Chris Ruffolo's Pick: Clemson -1.5

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