Notre Dame vs Louisville Prediction College Basketball Picks 2/21/24

Louisville (8-18) vs Notre Dame (9-16)

Game Info: Wednesday, February 21, 2024 at 7:00 pm (KFC Yum! Center)

Betting Odds: Louisville Cardinals -1 -- Over/Under: 135 Click Here for the Latest Odds

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The Notre Dame Fighting Irish and the Louisville Cardinals meet Wednesday in college basketball action from KFC Yum! Center. Notre Dame beat Georgia Tech in their last outing, improving to 9-16 overall. As for Louisville, they’re 8-18 on the season after a loss to Pittsburgh on Saturday. Let’s get into our Notre Dame vs. Louisville prediction. Check back all season long for free college basketball picks at Pick Dawgz.

Notre Dame Fighting Irish

The Irish got off to a rough 7-9 start this year, then took a losing streak versus Florida State, Boston College, Miami, Boston College again, Virginia, Pittsburgh and Duke in the next seven games. Notre Dame has won their last pair versus Virginia Tech and Georgia Tech, however.

In the Georgia Tech game last Wednesday, the Irish came out of halftime with a 31-28 edge. Notre Dame kept the pace from there on 27 more points and took the eventual victory 58-55. Markus Burton was the leading scorer on the team with 18 points, five steals and five assists.

Louisville Cardinals

Over on the Louisville side, they started out at 6-9 overall before losses to NC State, North Carolina, Wake Forest, Duke, Virginia and Clemson. The Cardinals are 2-3 since then with losses to Syracuse, Boston College and Pittsburgh mixed with wins over Florida State and Georgia Tech.

In the Pittsburgh game on Saturday, the Cardinals were down by double-digits at halftime. Louisville was drilled 49-32 the rest of the way and ended up losing 86-59 in the end. Kaleb Glenn was the lead scorer on 17 points, and Tre White doubled on 16 points with 11 boards.


I’ll lean toward Notre Dame in this one. Probably staying away, though; there’s not a lot to get excited about if you’re not a fan of either team. The Irish are coming off a win over Georgia Tech despite a miserable shooting outing with 31.6 percent from the field and 19.2 percent (5-of-26) from 3-point range. The good news is that Notre Dame had 40 rebounds and just six turnovers in that one, but they’ve got to get the offense going.

As for Louisville, they’ve had some pretty solid scoring efforts lately with 77 or more points in four of the last five games. I wouldn’t be surprised to see this one end up a fairly high-scoring, competitive game. Notre Dame probably has the inside track on a cover/win if all goes well, but it’s a coin flip.

Andrew’s Pick Notre Dame Fighting Irish +1

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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