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West Virginia vs Ohio Prediction 9/6/2025 Today’s College Football Picks

Ohio Bobcats quarterback Parker Navarro (13) looks for an open teammate, Thursday, August 28, 2025.

Ohio Bobcats quarterback Parker Navarro (13) looks for an open teammate, Thursday, August 28, 2025.

West Virginia (1-0) vs Ohio (0-1)

September 6, 2025 at 04:00 PM EDT

The Line: Betting Odds: Ohio +3 — Over/Under: +59.5

(Get latest betting odds)

The West Virginia Mountaineers and the Ohio Bobcats meet in week 2 college football action from Solich Field at Peden Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a West Virginia Mountaineers vs. Ohio Bobcats prediction.

West Virginia Mountaineers Recap

The West Virginia Mountaineers come into this game looking to add on to their 45-3 win over Robert Morris last time out to improve to 1-0 to start the year. After this game, West Virginia will head home for the Backyard Brawl against Pitt.

Mountaineers Looking To Keep Momentum Going

Nicco Marchiol threw for 224 yards and a touchdown on 17 of 20 passing while Jahiem White rushed for 93 yards and 2 touchdowns on 18 carries. Scotty Fox Jr. had 63 rushing yards with a TD while the aforementioned Marchiol had 56 rushing yards with a score and Cyncir Bowers had 54 rushing yards with a touchdown. Cam Vaughn led the Mountaineers with 7 catches for 126 yards and a touchdown in the win. On defense, Chase Wilson had a team-high 6 total tackles along with a sack while Reid Carrico had a sack and Hammond Russell IV had a pair of sacks and 2.5 TFLs.

Why the West Virginia Mountaineers will win

  • West Virginia has won eight of its last nine September games against non-AP-ranked teams.
  • The favorite has covered the spread in each of Ohio’s last four games at Peden Stadium.
  • Ohio has failed to cover the spread in three of its last four games against non-conference opponents.

Ohio Recap

The Ohio Bobcats come into this game looking to rebound from a 34-31 loss at the hands of Rutgers last time out to sit at 0-1 on the year. After this game, the Bobcats will head on the road for their big in-state rivalry game against Ohio State.

Bobcats Looking To Take Advantage of Home Spot

Parker Navarro threw for 239 yards and 3 TDs while also rushing for 93 yards and a touchdown. Sieh Bangura also rushed for 86 yards while Chase Hendricks led Ohio’s receiving group with 9 grabs for 115 yards while Jake Bruno had a pair of TD grabs and Mason Williams also had a touchdown reception of his own. On defense, Adonis Williams Jr. had a team-high 11 total tackles while Jay Crable added a sack for the Bobcats in the losing effort. 

Why the Ohio Bobcats will win

  • Ohio has won 17 of its last 18 games at Peden Stadium.
  • West Virginia has lost each of its last six road openers.
  • Ohio has covered the spread in seven of its last eight games.
  • West Virginia has failed to cover the spread in five of its last six road openers.

Total Points Facts

  • Eight of West Virginia’s last nine road games have gone OVER the total points line.
  • Each of Ohio’s last five home games in September have gone UNDER the total points line.

West Virginia Mountaineers vs. Ohio Bobcats Prediction

I’m going to lean towards Ohio here. I genuinely think that Ohio is live here with West Virginia having a prime look-ahead spot on deck with their matchup against Pitt forthcoming. Ohio battled Rutgers tough last week and I think at home, this Bobcats team is really dangerous. Give me Ohio and the points here.

Chris Ruffolo's Pick: Ohio +3

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