West Virginia (2-6) vs Houston (7-1)
November 1, 2025 at 12:00 PM EDT
The Line: Betting Odds: Houston -13.5 — Over/Under: +48.5
The West Virginia Mountaineers and the Houston Cougars meet in week 10 college football action from TDECU Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a West Virginia Mountaineers vs. Houston Cougars prediction.
West Virginia Mountaineers Recap
The West Virginia Mountaineers come into this game looking to rebound from a 23-17 loss at the hands of TCU last time out to sit at 2-6 this season. After this game, West Virginia will head home for a game against Colorado.
Mountaineers Drop 5 In A Row
Nicco Marchiol has thrown for 720 yards, 2 touchdowns and 2 INTs on 67.3% passing while Scotty Fox Jr. has thrown for 466 yards, 3 touchdowns and 2 picks on 59.1% passing and Khalil Wilkins has thrown for 176 yards, a TD and 2 INTs on 48.4% passing while also leading WVU in rushing with 243 yards and 2 touchdowns. Cam Vaughn leads West Virginia with 27 catches for 420 yards and 3 touchdowns while four more Mountaineers have 100+ receiving yards as well this season. On defense, Fred Perry leads West Virginia with 50 total tackles while Darrian Lewis and Chase Wilson each have 2 interceptions. As a unit, West Virginia’s defense has combined for 14 sacks and 8 interceptions this season.
Houston Cougars Recap
The Houston Cougars come into this game looking to add on to their 24-16 win over Arizona State last time out to sit at 7-1 this season. After this game, Houston will head on the road for a game against UCF.
Cougars Win 3 Straight
Conner Weigman has thrown for 1,581 yards, 12 touchdowns and 2 interceptions on 63.7% passing while Dean Connors has rushed for 586 yards and 4 TDs on the ground this season. Weigman has 354 rushing yards and 8 rushing TDs. Amare Thomas leads the Cougars with 535 receiving yards and 4 touchdowns while Stephon Johnson has 275 receiving yards and 2 TDs and Tanner Koziol has 450 receiving yards and 4 scores as well this season. On defense, Jalen Garner has a team-high 53 total tackles while Eddie Walls III has a team-high 5.5 sacks. As a unit, Houston’s defense has combined for 21 sacks and 6 interceptions so far this season.
West Virginia Mountaineers @ Houston Cougars Betting Trends: Week 10
Why the Houston Cougars will win
- West Virginia has lost each of its last 11 games against AP-ranked teams.
- Houston has won each of its last six games against non-AP-ranked teams.
- West Virginia has failed to cover the spread in 10 of its last 11 November games against AP-ranked teams.
- Houston has covered the spread in each of its last four games as a favorite in Texas.
- West Virginia has lost the first half in each of its last six games against conference opponents.
Why the West Virginia Mountaineers will win
- Houston has lost each of its last four November games against non-AP-ranked teams.
- The road team has won four of Houston’s last five games.
- Houston has failed to cover the spread in each of its last four November games as a favorite.
- The road team has covered the spread in three of Houston’s last four games.
Total Points Facts
- Each of Houston’s last five games against non-AP-ranked teams have gone OVER the total points line.
- Each of West Virginia’s last four road games against AP-ranked teams have gone OVER the total points line.
Houston Cougars Player Prop Facts
- Heading into Week 10, Dean Connors leads the Big 12 Conference for rush attempts (135) this season.
West Virginia Mountaineers Player Prop Facts
- Heading into Week 10, Cam Vaughn leads West Virginia for touchdowns (3) this season.
Matchup/League Facts
- Houston ranks 1st among FBS teams for Q3 opponent points per game this season (0.8).
- Houston is one of only seven FBS teams undefeated in road games this season (4-0).
- West Virginia ranks 134th among FBS teams for H1 points per game this season (6.4).
- West Virginia ranks 133rd among FBS teams for Q1 points per game this season (1.8).
West Virginia Mountaineers vs. Houston Cougars Prediction
I’m on Houston here. I think Houston might be one of my least favorite 7-1 teams I’ve laid eyes on, but they keep finding ways to get the job done and maybe this game is more of a fade of West Virginia more than anything else but I’m rolling with Houston in this one.