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UTSA vs USF Prediction 11/6/2025 Today’s College Football Picks

Oct 25, 2025; Memphis, Tennessee, USA; South Florida Bulls quarterback Byrum Brown (17) runs with the ball against the Memphis Tigers during the second half at Simmons Bank Liberty Stadium. Mandatory Credit: Wesley Hale-Imagn Images

Oct 25, 2025; Memphis, Tennessee, USA; South Florida Bulls quarterback Byrum Brown (17) runs with the ball against the Memphis Tigers during the second half at Simmons Bank Liberty Stadium. Mandatory Credit: Wesley Hale-Imagn Images

MATCHUP UTSA Roadrunners South Florida Bulls
Team Records 4-5 7-2
Where Raymond James Stadium, Tampa, FL
When Thursday, November 6, 2025
Time 07:30 PM EST
TV ESPN
The UTSA Roadrunners and South Florida Bulls meet Thursday in college football action at Jones AT&T Stadium. Here’s a UTSA vs USF Prediction. This article will include a UTSA vs USF Pick.

UTSA Roadrunners Betting Preview


The UTSA Roadrunners lost to North Texas, beat Tulane, and play Charlotte next. UTSA has split its last 8 games. Owen McCown is completing 67.5 percent of his passes for 1,680 yards, 17 touchdowns, and 4 interceptions. Devin McCuin and AJ Wilson have combined for 795 receiving yards and 9 touchdowns, while David Amador II has 28 receptions.

The UTSA Roadrunners ground game is averaging 203.7 yards per contest, and Robert Henry Jr. leads the way with 955 yards and 9 touchdowns. Defensively, UTSA is allowing 30.9 points and 459 yards per game. Shad Banks Jr. leads the UTSA Roadrunners with 51 tackles, Nnanna Anyanwu has 5 sacks and Davin Martin has 1 interception.

South Florida Bulls Betting Preview


The South Florida Bulls lost ot Memphis, beat FAU, and play Navy next. The South Florida Bulls have won 4 of their last 5 games. Byrum Brown is completing 62.9 percent of his passes for 1,964 yards, 17 touchdowns, and 6 interceptions. Chas Nimrod and Keshaun Singleton combined for 917 receiving yards and 6 touchdowns, while Jeremiah Koger has 17 receptions.

The South Florida Bulls ground game is averaging 225.5 yards per contest, and Byrum Brown leads the way with 596 yards and 8 touchdowns. Defensively, South Florida is allowing 24.4 points and 387.3 yards per game. Mac Harris leads the South Florida Bulls with 69 tackles, Rico Watson III has 2 sacks and James Chenault has 2 interceptions.

Why the South Florida Bulls will win

Why the UTSA Roadrunners will win

Total Points Facts

South Florida Bulls Player Prop Facts

UTSA Roadrunners Player Prop Facts

Matchup/League Facts

UTSA vs USF Prediction


USF is obviously the better, more talented team with one of the better offenses in the country, but double-digit chalk is risky on a weekday. Also, while UTSA doesn’t play a lick of defense, it’s an above average offensive side that’s 26th in total offense, and should be able to take advantage of a South Florida defense that’s 124th against the pass. UTSA has topped 40 points in 3 of its last 6 games. The Roadrunners don’t need oddsmakers help with a boatload of points. Give me UTSA and the free points.

Randy Chambers's Pick: UTSA +14

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