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UL Monroe vs Alabama Prediction 9/6/2025 Today’s College Football Picks

Aug 30, 2025; Tallahassee, Florida, USA;  Alabama Crimson Tide quarterback Ty Simpson (15) during warmups before the game between the Florida State Seminoles and the Alabama Crimson Tide at Doak S. Campbell Stadium. Mandatory Credit: Melina Myers-Imagn Images

Aug 30, 2025; Tallahassee, Florida, USA; Alabama Crimson Tide quarterback Ty Simpson (15) during warmups before the game between the Florida State Seminoles and the Alabama Crimson Tide at Doak S. Campbell Stadium. Mandatory Credit: Melina Myers-Imagn Images

UL Monroe (1-0) vs Alabama (0-1)

September 6, 2025 at 07:45 PM EDT

The Line: Betting Odds: Alabama -36.5 — Over/Under: 50.5

(Get latest betting odds)

Louisiana-Monroe and Alabama meet Saturday in college football action from Bryant Denny. Here’s a Louisiana-Monroe vs Alabama prediction. We will look at this from a betting perspective and determine the best Louisiana-Monroe Warhawks vs Alabama Crimson Tide pick. We will examine:

The Louisiana-Monroe Warhawks’ recent form and player performance

The Alabama Crimson Tide’ recent form and player performance

Recent betting trends and streaks involving the Warhawks

Recent betting trends and streaks involving the Crimson Tide

Recent betting trends in games played between Louisiana-Monroe and Alabama

A summary that ties it all together and produces a favorable betting outcome for the Louisiana-Monroe vs Alabama game.

Is the Alabama Dynasty Done?


There is some major concern surrounding this Alabama program right now, and if they don’t win this game in blowout fashion, there is going to be even more rumblings. Alabama scored 17 points against Florida State but the defense gave up 31 points, and it was a bit of a shocking loss as they came into the game as 14 point favorites. This is a team that has star power, but on defense they didn’t look all that interested in playing defense. 

On offense, Alabama was led by Ty Simpson and who completed 23 of his 43 passes for 254 yards and two touchdowns. Germie Bernard was a star out wide and he caught eight passes for 146 yards. Alabama also didn’t have the explosive running game, and that will need to be found here. Kevin Riley finished with five carries for 31 yards. 

Why Alabama Will Beat Louisiana-Monroe

Louisiana-Monroe has lost each of its last 17 road games against opponents from the Southeastern Conference.
Alabama has won each of its last 12 games at Saban Field at Bryant-Denny Stadium.
Louisiana-Monroe has failed to cover the spread in each of its last five games.
The team ranked 21st in the AP Poll has covered the spread in five of its last six games.
Alabama has won the first half in each of its last four games against non-conference opponents at Saban Field at Bryant-Denny Stadium.

Strong First Game for Louisiana-Monroe


It was a strong first game for Louisiana-Monroe, and they were able to pick up the victory over St. Francis. The offense was pretty consistent putting up 29 points, and even more dominant was the defense that gave up zero points. The Warhawks gave up only 131 total yards, and only 50 of those were through the air. Compare that to Louisiana-Monroe who had 311 rushing yards as a team. Braylon McReynolds was the top rusher, putting up 113 yards on 11 carries. Aidan Armenta was under center and he completed 12 of his 23 passes for 95 yards, one touchdown, and one interception. 

The defense was good, but this is a much bigger test here. Louisiana-Monroe really needs to do everything in its power to make Alabama one-dimensional. Are they going to shut them down? Probably not. If they can make away one though, it’s going to put a lot of pressure on the Crimson Tide. 

Matchup/League Facts


Alabama ranks T116th among FBS teams for Q2 points per game this season (0.0).
Alabama ranks 111th among FBS teams for rushing yards per game this season (87.0).
Louisiana-Monroe ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).
Louisiana-Monroe ranks T1st among FBS teams for Q3 opponent points per game this season (0.0).

Louisiana-Monroe vs Alabama Prediction

Is Alabama’s dynasty dead? I think it might be, but even teams that aren’t in the middle of a dynasty, can beat up on a team like Louisiana-Monroe. The Warhawks defense looked impressive in the first game, but I do think Alabama’s balanced attack is going to be a lot better here. Alabama is going to get the running game going, and Louisiana-Monroe is going to have no answer. Alabama is going to put up at least 55 points here, and that will be enough for them to cover the spread. Back Alabama to win and cover the spread.

Shane Mickle's Pick: Alabama -36.5

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