South Florida vs UAB Prediction 11/22/2025 Today’s College Football Picks
Chris Ruffolo
Nov 1, 2025; East Hartford, Connecticut, USA; UAB Blazers quarterback Jalen Kitna (7) hands off the ball against the UConn Huskies in the first quarter at Pratt & Whitney Stadium at Rentschler Field. Mandatory Credit: David Butler II-Imagn Images
MATCHUP
South Florida Bulls
UAB Blazers
Team Records
7-3
3-7
Spread
-21.5 -112
+21.5 -108
Moneyline
-2100
+1100
Total
Over 68.5 (-110)
Under 68.5 (-110)
Where
Protective Stadium, Birmingham, AL
When
Saturday, November 22, 2025
Time
03:00 PM EST
TV
ESPN+
The USF Bulls and the UAB Blazers meet in week 13 college football action from Protective Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a USF Bulls vs. UAB Blazers prediction.
USF Bulls Recap
The USF Bulls come into this game looking to rebound from a 41-38 loss at the hands of Navy last time out to sit at 7-3 on the year. After this game, USF will head home for their season finale against Rice.
Bulls Alternate Wins & Losses In 4 Straight
Byrum Brown has thrown for 2,530 yards, 21 touchdowns and 7 interceptions on 65.4% passing while also leading USF in rushing with 841 rushing yards and 11 scores. Sam Franklin has 378 rushing yards and 4 touchdowns and Nykahi Davenport has 425 rushing yards with 5 TDs as well. Alvon Isaac has 282 rushing yards as well while Keshaun Singleton has a team-high 38 receptions for 659 yard and 6 touchdowns. Jeremiah Koger has 28 grabs for 467 yards with 6 TDs and Chas Nimrod has 23 catches for 466 yards and 3 scores. On defense, Mac Harris has a team-high 90 total tackles and a team-high 6 sacks. James Chenault and Jarvis Lee each have a pair of interceptions as well for the Bulls’ defense this season. As a unit, USF has combined for 26 sacks and 11 interceptions so far this season.
UAB Blazers Recap
The UAB Blazers come into this game looking to bounce back from a 53-24 loss at the hands of North Texas last time out to sit at 3-7 this season. After this game, UAB will head on the road for a game against Tulsa.
Blazers Drop 3 In A Row
Jalen Kitna has thrown for 2,066 yards, 11 touchdowns and 7 interceptions on 66.8% passing while Ryder Burton’s thrown for 687 yards, 7 touchdowns and 4 INTs on 64.9% passing. Jevon Jackson has a team-high 751 rushing yards with 3 touchdowns while Solomon Beebe and Isaiah Jacobs each have 200+ rushing yards and a combined 8 rushing TDs this season. Iverson Hooks leads UAB’s receiving group with 57 catches for 735 yards and 6 touchdowns while Brandon Hawkins Jr. has 38 grabs for 500 yards and 4 touchdowns and Corri Milliner has 341 receiving yards with 2 TDs. On defense, Devin Hightower has a team-high 70 total tackles while the UAB defense as a whole has combined for 14 sacks and 3 interceptions so far this season.
South Florida Bulls @ UAB Blazers Betting Trends: Week 13
Why the UAB Blazers will win
South Florida has lost 14 of its last 16 road games in November.
The home team has won seven of South Florida’s last eight games.
The home team has covered the spread in each of South Florida’s last four games.
South Florida has failed to cover the spread in five of its last six November games as a road favorite.
Why the South Florida Bulls will win
UAB has lost each of its last five games against non-AP-ranked teams.
The favorite has won nine of UAB’s last 10 games.
UAB has failed to cover the spread in each of its last six games against non-AP-ranked teams.
The favorite has covered the spread in five of UAB’s last six games.
South Florida has won the first quarter in three of its last four games against conference opponents.
South Florida has won the first half in three of its last four games against conference opponents.
Total Points Facts
Each of South Florida’s last eight road games in November have gone OVER the total points line.
Each of UAB’s last four games against teams from Florida have gone OVER the total points line.
UAB Blazers Player Prop Facts
Heading into Week 13, Solomon Beebe ranks 8th amongst FBS players for kick return yards (463) this season.
South Florida Bulls Player Prop Facts
Heading into Week 13, Chas Nimrod ranks 6th amongst qualified players for Yards Per Reception (20.3) this season.
Matchup/League Facts
UAB ranks 136th among FBS teams for Q1 opponent points per game this season (12.2).
UAB ranks 136th among FBS teams for H1 opponent points per game this season (23.5).
South Florida ranks 1st among FBS teams for H2 points per game this season (22.0).
South Florida has averaged 50.3 points over its last seven games – most in the FBS over that span.
USF Bulls vs. UAB Blazers Prediction
I’m on the over here. I just don’t know where either of these teams are at in this game, with USF pretty much playing out the string now that all hope for an AAC title is pretty much gone, and UAB has no chance of going for a bowl game. What I do know is that both teams can score if they want to and both defenses have been more than susceptible this season so give me the over here.