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Rice vs Charlotte Prediction 9/18/2025 Today’s College Football Picks

Aug 29, 2025; Charlotte, North Carolina, USA; Charlotte 49ers running back CJ Stokes (23) is tackled by Appalachian State Mountaineers defensive back Zyeir Gamble (5) during the second half at Bank of America Stadium. Mandatory Credit: Jim Dedmon-Imagn Images

Aug 29, 2025; Charlotte, North Carolina, USA; Charlotte 49ers running back CJ Stokes (23) is tackled by Appalachian State Mountaineers defensive back Zyeir Gamble (5) during the second half at Bank of America Stadium. Mandatory Credit: Jim Dedmon-Imagn Images

Rice (2-1) vs Charlotte (1-2)

September 18, 2025 at 07:30 PM EDT

The Line: Betting Odds: Charlotte +2.5 — Over/Under: +42.5

(Get latest betting odds)

The Rice Owls and Charlotte 49ers meet Thursday in college football action at Jerry Richardson Stadium. Here’s a Rice vs Charlotte Prediction. This article will include a Rice vs Charlotte Pick.

Rice Owls Betting Preview

The Rice Owls beat Prairie View A&M, lost to Houston, and will play FAU next. The Rice Owls have split their last 10 games. Chase Jenkins is completing 73 percent of his passes for 182 yards, 1 touchdown, and 1 interception. Drayden Dickmann and Landon Ransom-Goelz have combined for 141 receiving yards and 1 touchdown, while Aaron Turner has 7 receptions.

The Rice Owls ground game is averaging 243.3 yards per contest, and Quinton Jackson leads the way with 213 yards and 2 touchdowns. Defensively, Rice is allowing 21.3 points and 294 yards per game. Ty Morris leads the Rice Owls with 20 tackles, Jospeh Mutombo has 1.5 sacks and Jack Kane has 1 interception.

Charlotte 49ers Betting Preview

The Charlotte 49ers lost to North Carolina, beat Monmouth, and they play USF next. Charlotte has lost 6 of its last 9 games. Conner Harrell is completing 67.5 percent of his passes for 664 yards, 4 touchdowns, and 2 interceptions. E. Jai Mason and Javen Nicholas have combined for 461 receiving yards and 3 touchdowns, while Miles Burris has 6 receptions.

The Charlotte 49ers ground game is averaging 92.7 yards per contest, and CJ Stokes leads the way with 96 yards on 32 carries. Defensively, Charlotte is allowing 29.7 points and 449 yards per game. Ja’Qurious Conley leads the Charlotte 49ers with 20 tackles, Reid Williford has 2 sacks and Dwight Bootle II has 1 pass deflection.

Rice Owls @ Charlotte 49ers Betting Trends: Week 4

Charlotte 49ers Player Prop Facts

  • Heading into Week 4, E. Jai Mason leads the American Conference for receiving yards (284) this season.

Rice Owls Player Prop Facts

  • Heading into Week 4, Chase Jenkins leads Rice for touchdowns (2) this season.

Matchup/League Facts

  • Charlotte ranks 133rd among FBS teams for red zone percentage this season (54.5).
  • Charlotte ranks 129th among FBS teams for 1st downs against this season (75).
  • Rice ranks 14th among FBS teams for rushing yards per game this season (243.3).
  • Rice ranks T119th among FBS teams for H2 points per game this season (6.7).

Rice vs Charlotte Prediction

Quick turnaround for both teams, there’s value to getting points with home teams in these spots. However, Charlotte hasn’t shown much through three games, as it doesn’t finish drives offensively and can’t run the ball. Charlotte also hasn’t been good defensively. Rice has been able to win the games it’s supposed to win this season and while it has its struggles as well, it is a top-20 rushing offense, which is a recipe to win on the road.

It’s weird seeing Rice in the favorite role, but it’s hard to be confident in Charlotte, a team that’s also 4-8 ATS in its last 12 games as an underdog. It might be ugly, but Rice should be able to suck the life out of the stadium and grind out a win. I’ll lay the small number.

Randy Chambers's Pick: Rice -2

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