Oklahoma vs Alabama Prediction 11/15/2025 Today’s College Football Picks
Chris Ruffolo
Oklahoma quarterback John Mateer (10) points toward the Oklahoma section after a fourth quarter touchdown during a college football game between Tennessee and Oklahoma in Neyland Stadium in Knoxville on Nov. 1, 2025.
MATCHUP
Oklahoma Sooners
Alabama Crimson Tide
Team Records
7-2
8-1
Spread
+6 -112
-6 -108
Moneyline
+185
-225
Total
Over 45.5 (-112)
Under 45.5 (-108)
Where
Bryant-Denny Stadium, Tuscaloosa, AL
When
Saturday, November 15, 2025
Time
03:30 PM EST
TV
ABC
The Oklahoma Sooners and the Alabama Crimson Tide meet in week 12 college football action from Bryant Denny Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Oklahoma Sooners vs. Alabama Crimson Tide prediction.
Oklahoma Sooners Recap
The Oklahoma Sooners come into this game looking to add on to their 33-27 win over Tennessee last time out to improve to 7-2 this season. After this game, Oklahoma will head home for a game against the Missouri Tigers.
Sooners Looking To Keep Playoff Hopes Alive
John Mateer has thrown for 1,949 yards, 8 touchdowns and 7 interceptions on 63.8% passing while also rushing for 306 yards and 6 touchdowns and Tory Blaylock also has a team-high 401 rushing yards and 4 TDs while Xavier Robinson has 332 rushing yards and 4 TDs as well this season. Isaiah Sategna III has a team-high 49 receptions for 692 yards and 5 TDs while Jaren Kanak has 410 receiving yards. Deion Burks has 435 receiving yards and Keontez Lewis has 226 receiving yards as well this season. On defense, Kip Lewis has a team-high 53 total tackles while R Mason Thomas has a team-high 6.5 sacks and Taylor Wein has 3.5 sacks. Jayden Jackson and Gracen Halton each have 3 sacks as well for Oklahoma this season. As a unit, Oklahoma has combined for 33 sacks and 5 interceptions this season.
Alabama Crimson Tide Recap
The Alabama Crimson Tide come into this game looking to build on their 20-9 win over LSU last time out to sit at 8-1 this season. After this game, Alabama will take on Eastern Illinois at home.
Crimson Tide Looking To Keep Up Winning Ways At Home
Ty Simpson has thrown for 2,461 yards, 21 touchdowns and an interception on 66.9% passing while Jam Miller leads the Crimson Tide in rushing with 321 yards and 2 TDs. Germie Bernard has a team-high 41 catches for 605 yards and 6 touchdowns while Ryan Williams has 528 receiving yards with 4 TDs and Isaiah Horton has 298 receiving yards and 5 TDs. Lotzeir Brooks has 322 receiving yards while Josh Cuevas has 261 receiving yards and two more Crimson Tide receivers have 100+ receiving yards as well this season. On defense, Justin Jefferson has a team-high 54 total tackles including 33 solo tackles while Bray Hubbard has a team-high 3 interceptions. Yhonzae Pierre has a team-high 6 sacks and LT Overton has 4 sacks as well this season. As a unit, Alabama’s defense has combined for 18 sacks and 8 interceptions so far this season.
Alabama has won each of its last 24 games against conference opponents at Saban Field at Bryant-Denny Stadium.
Oklahoma has lost seven of its last nine road games in November.
Alabama has covered the spread in each of its last eight home games.
Oklahoma has failed to cover the spread in eight of its last nine road games in November.
Alabama has won the first quarter in seven of its last eight games against conference opponents at Saban Field at Bryant-Denny Stadium.
Alabama has won the first half in each of its last four games against conference opponents.
Why the Oklahoma Sooners will win
Oklahoma has won four of its last five November games as an underdog against top-15 AP-ranked teams.
Oklahoma has covered the spread in five of its last six games against AP-ranked teams.
The team ranked 4th in the AP Poll has failed to cover the spread in eight of its last 10 games.
Oklahoma has won the first half in three of its last four games against conference opponents.
Total Points Facts
Each of Oklahoma’s last six November games as a road underdog have gone OVER the total points line.
Each of Alabama’s last five home games against conference opponents have gone UNDER the total points line.
Alabama Crimson Tide Player Prop Facts
Heading into Week 12, Ty Simpson ranks 2nd in the league for TD:INT ratio (21.00) this season.
Oklahoma Sooners Player Prop Facts
Heading into Week 12, Tate Sandell ranks T6th amongst FBS players for made field goals (18) this season.
Matchup/League Facts
Alabama has won the second quarter in each of its last eight games – longest active streak in the FBS.
Alabama ranks T8th among FBS teams for average point differential in second quarters this season (+7.3).
Oklahoma ranks T1st among FBS teams for red zone percentage this season (100.0).
Oklahoma ranks 4th among FBS teams for rushing yards allowed per game this season (82.4).
Oklahoma Sooners vs. Alabama Crimson Tide Prediction
I’m on the under in this one. I just think this has the makings of a true SEC black and blue kind of game. The Sooners have one of the best defensive units in the country, and I’m still not sold that John Mateer is fully healthy for the Sooners under center, and now has to go against a solid Alabama defense. Feels like a 24-17 kind of game, so give me the under in this one.
