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Ohio State vs Michigan Prediction 11/29/2025 Today’s College Football Picks

Ohio State Buckeyes quarterback Julian Sayin (10) speaks to his teammates in the second half of the NCAA college football game at Ohio Stadium on Saturday, Nov. 15, 2025 in Columbus, Ohio.

Ohio State Buckeyes quarterback Julian Sayin (10) speaks to his teammates in the second half of the NCAA college football game at Ohio Stadium on Saturday, Nov. 15, 2025 in Columbus, Ohio.

MATCHUP Ohio State Buckeyes Michigan Wolverines
Team Records 11-0 9-2
Spread -10 -108 +10 -112
Moneyline -395 +310
Total Over 43.5 (-115) Under 43.5 (-105)
Where Michigan Stadium, Ann Arbor, MI
When Saturday, November 29, 2025
Time 12:00 PM EST
TV FOX

The Ohio State Buckeyes and the Michigan Wolverines meet in week 14 college football action from Michigan Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Ohio State Buckeyes vs. Michigan Wolverines prediction.

Ohio State Buckeyes Recap

The Ohio State Buckeyes come into this game looking to add on to their 42-9 win over Rutgers last time out to sit at 11-0 on the year. 

Buckeyes Looking To Punch Ticket To Big Ten Title Game

Julian Sayin has thrown for 2,832 yards, 27 touchdowns and 4 interceptions on 79.4% passing while Bo Jackson has rushed for 835 yards and 5 touchdowns and CJ Donaldson has 286 rushing yards with 10 touchdowns and James Peoples has 344 rushing yards. Jeremiah Smith leads Ohio State’s receiving group with 69 grabs for 902 yards and 10 touchdowns while Carnell Tate has 39 grabs for 711 yards and 7 touchdowns and Max Klare has 400 receiving yards and 2 touchdowns. On defense, Sonny Styles ahas a team-high 63 total tackles with Styles logging 35 solo tackles while Arvell Reese has 6.5 sacks. Caden Curry has a team-high 9 sacks while Kenyatta Jackson Jr. has 4.5 sacks. As a unit, Ohio State’s defense has combined for 29 sacks and 6 interceptions so far this season. 

Michigan Wolverines Recap

The Michigan Wolverines come into this game looking to add on to their 45-20 win over Maryland last time out to sit at 9-2 this season.

Wolverines Hoping To Crash Playoff Party

Bryce Underwood has thrown for 2,166 yards, 9 touchdowns and 5 interceptions on 62.2% passing while Justice Haynes has 857 rushing yards and 10 touchdowns this season. Jordan Marshall has a team-high 871 rushing yards and 10 touchdowns while Andrew Marsh has 42 catches for a team-high 641 receiving yards and 3 touchdowns this season. Two more Michigan receivers have 200+ receiving yards and another pair of Wolverines have 100+ receiving yards as well this season. On defense, Ernest Hausmann has a team-high 68 total tackles while Cole Sullivan has 3 interceptions and a pair of sacks. Derrick Moore has a team-high 9.5 sacks while Jaishawn Barham has 4 sacks as well this season. As a unit, Michigan’s defense has combined for 28 sacks and 12 interceptions so far this season.

Ohio State Buckeyes @ Michigan Wolverines Betting Trends: Week 14

Why the Michigan Wolverines will win

Why the Ohio State Buckeyes will win

Total Points Facts

Michigan Wolverines Player Prop Facts

Ohio State Buckeyes Player Prop Facts

Matchup/League Facts

Ohio State Buckeyes vs. Michigan Wolverines Prediction

I’m on the under in this game. I think whichever way this game goes, it’s low-scoring. Whether it’s Michigan not being able to break down Ohio State’s defense or the Buckeyes prioritizing health with the Big Ten and possibly college football playoff on the horizon I think points will be at a premium here. Give me the under.

Chris Ruffolo's Pick: Under 43.5

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