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Northwestern vs Nebraska Prediction 10/25/2025 Today’s College Football Picks

Sep 27, 2025; Evanston, Illinois, USA; UCLA Bruins defensive back Rodrick Pleasant (18) defends Northwestern Wildcats wide receiver Hayden Eligon II (80) during the second half at Northwestern Medicine Field at Martin Stadium. Mandatory Credit: David Banks-Imagn Images

Sep 27, 2025; Evanston, Illinois, USA; UCLA Bruins defensive back Rodrick Pleasant (18) defends Northwestern Wildcats wide receiver Hayden Eligon II (80) during the second half at Northwestern Medicine Field at Martin Stadium. Mandatory Credit: David Banks-Imagn Images

MATCHUP Northwestern Wildcats Nebraska Cornhuskers
Team Records 5-3 6-2
Where Memorial Stadium (Lincoln, NE), Lincoln, NE
When Saturday, October 25, 2025
Time 12:00 PM EDT
TV FS1

In this article, we will formulate a Northwestern vs Nebraska Prediction for this College Football Week 9 game on Saturday, October 25th. Let’s take a look at the prediction for this College Football matchup.

Nebraska Cornhuskers Preview

Nebraska has a 5-2 record this season and is sitting 10th in the Big Ten. They are 2-5 ATS, 5-2 in Over/Under and have a 3-1 home record and a 1-1 away record. Nebraska is coming off a 6-24 road loss against Minnesota and will face USC, UCLA and Penn State next.

Offensively, Nebraska averages 36 points per game, ranking 29th in the nation, while defensively, they allow 19.4 points per game, which is 30th. Nebraska averages 416.1 total yards per game (291.1 passing and 125 rushing), while allowing 279.3 total yards per game (156.3 rushing and 123.0 passing).

Dylan Raiola leads Nebraska with 1,768 passing yards with 72.8% completed passes and 16 touchdowns. Emmett Johnson leads the team in rushing yards with 713, while Nyziah Hunter has a team-high 27 receptions for 455 receiving yards. Defensively, Javin Wright has a team-high 51 total tackles (23 of them solo), while Dasan McCullough leads the team in sacks, with 2.0, and DeShon Singleton has a team-high 2 interceptions.

Northwestern Wildcats Preview

Northwestern has a 5-2 record this season and is sitting 4th in the Big Ten. They are 5-2 ATS, 1-6 in Over/Under and have a 4-1 home record and a 1-1 away record. Northwestern is coming off a 19-0 home win against Purdue and will face USC, Michigan and Minnesota next.

Offensively, Northwestern averages 22.7 points per game, ranking 100th in the nation, while defensively, they allow 15.1 points per game, which is 11th. Northwestern averages 364.4 total yards per game (174.3 passing and 190.1 rushing), while allowing 305.3 total yards per game (136.7 rushing and 168.6 passing).

Preston Stone leads Northwestern with 1,213 passing yards with 59.4% completed passes and 10 touchdowns. Caleb Komolafe leads the team in rushing yards with 483, while Griffin Wilde has a team-high 36 receptions for 516 receiving yards. Defensively, Robert Fitzgerald has a team-high 60 total tackles (36 of them solo), while Anto Saka leads the team in sacks, with 3.0, and Mac Uihlein has a team-high 3 interceptions.

Northwestern Wildcats @ Nebraska Cornhuskers Betting Trends: Week 9

Why the Nebraska Cornhuskers will win

Why the Northwestern Wildcats will win

Total Points Facts

Nebraska Cornhuskers Player Prop Facts

Northwestern Wildcats Player Prop Facts

Matchup/League Facts

Northwestern vs Nebraska Prediction

In their previous meeting in 2023, Nebraska won 17-9 at home and both teams are tied 5-5 in their last 10 meetings. Nebraska has won its last three home meetings against Northwestern.

In this Northwestern vs Nebraska Prediction, Nebraska is coming as -7-point home favorites, with the total set at 43 points. Both teams have identical records this season, but Nebraska has been terrible against the spread, having failed to cover its last four games. On the flip side, Northwestern is 5-1 against the spread in their last 6 games and I expect it to keep this one close. Take Northwestern and the +7 points in this one.

Nikos Lagouretos's Pick: Northwestern +7

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