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Northern Illinois vs Toledo Prediction 11/5/2025 Today’s College Football Picks

Oct 25, 2025; Pullman, Washington, USA; Toledo Rockets quarterback Tucker Gleason (4) throws a pass against the Washington State Cougars in the first half at Gesa Field at Martin Stadium. Mandatory Credit: James Snook-Imagn Images

Oct 25, 2025; Pullman, Washington, USA; Toledo Rockets quarterback Tucker Gleason (4) throws a pass against the Washington State Cougars in the first half at Gesa Field at Martin Stadium. Mandatory Credit: James Snook-Imagn Images

Northern Illinois (2-6) vs Toledo (4-4)

November 5, 2025 at 07:00 PM EST

The Line: Betting Odds: Toledo -14.5 — Over/Under: +42.5

(Get latest betting odds)

In this article we will formulate a Northern Illinois vs Toledo prediction for this College Football game on Wednesday, November 5th at the Glass Bowl in Toledo, Ohio. Let’s take a look at the prediction for this week 11 matchup. 

Northern Illinois Huskies Betting Preview

The Northern Illinois Huskies are 2-6 (1-3) this year after they defeated Ball State by a score of 21-7 in their last game. Northern Illinois was tied at seven at halftime, but they pitched a shutout in the second half to get the low scoring win. The Huskies out gained Ball State by a total of 370-275, went 9-16 on third downs, and tied the turnover battle at three in the game. Josh Holst went 6-11 for 65 yards, one touchdown, and one interception, while Chavon Wright rushed 37 times for 166 yards. DeAree Rogers led the receivers with three catches for 43 yards and one score in the game. The NIU defense recorded four sacks and five tackles for loss in the win. 

Prior to that game, Northern Illinois lost to Ohio by a score of 48-21 and Eastern Michigan by a score of 16-10. The Huskies have lost six of their last seven games and they are currently near the bottom of the MAC standings. Northern Illinois has scored 13.4 points per game with 103.1 passing yards and 173.0 rushing yards per game, while they have allowed 22.1 points against per game this season. Josh Holst has thrown for 602 yards, four touchdowns, and three interceptions, while Telly Johnson has rushed for 581 yards and three scores on 93 carries this year. 

Toledo Rockets Betting Preview

The Toledo Rockets are 4-4 (2-2) this season after they lost to Washington State by a score of 28-7 in their last game. Toledo cut the deficit to 21-7 right before halftime, but failed to score any points in the second half for the loss. The Rockets were out gained by a total of 321-299, went 6-16 on third downs, and won the turnover battle by a total of 2-1 in the game. Tucker Gleason went 26-41 for 238 yards, one touchdown, and one interception, while Kenji Christian rushed 11 times for just 33 yards. Jacob Petersen led the receivers with five catches for 58 yards in the loss. The Toledo defense recorded two sacks and five tackles for loss in the game. 

Prior to that game, Toledo defeated Kent State by a score of 45-10, but did lose to Bowling Green by a score of 28-23 before that. The Rockets have alternated wins and losses over their last six games and they are currently tied for sixth in the MAC standings. Toledo has scored 31.8 points per game with 253.3 passing yards and 183.3 rushing yards per game, while they have allowed 16.0 points against per game this season. Tucker Gleason has thrown for 1,721 yards, 13 touchdowns, and five interceptions, while Junior Vandeross III has 52 receptions for 608 yards and eight scores this season. 

Matchup/League Facts

  • Toledo ranks 3rd among FBS teams for yards allowed per game this season (237.6).
  • Toledo ranks 134th among FBS teams for 4th down conversion percentage this season (21.4).
  • Northern Illinois ranks 134th among FBS teams for points per game this season (13.4).
  • Northern Illinois ranks T134th among FBS teams for Q2 points per game this season (3.0).

Northern Illinois vs Toledo Prediction 

Toledo comes into this matchup after a disappointing loss against Washington State, but they play their best football at home and should win here. The Rockets are the much better offensive team in this contest and they have scored 45 points in their last two home games. Northern Illinois did snap their losing streak with a win over Ball State last time out, but they are one of the lowest scoring teams in the country and their passing attack is not good. Take Toledo to win and cover here.

David Racey's Pick: Toledo -14.5

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