Minnesota (3-1) vs Ohio State (4-0)
October 4, 2025 at 07:30 PM EDT
The Line: Betting Odds: Ohio State -24 — Over/Under: +44.5
The Minnesota Golden Gophers and Ohio State Buckeyes meet Saturday in college football action at Ohio Stadium. Here’s a Minnesota vs Ohio State Prediction. This article will include a Minnesota vs Ohio State Pick.
Minnesota Golden Gophers Betting Preview
The Minnesota Golden Gophers lost to Cal, beat Rutgers, and they play Purdue next. Minnesota has won 5 of its last 6 games. Drake Lindsey is completing 65.8 percent of his passes for 958 yards, 7 touchdowns, and 2 interceptions. Javon Tracy and Jalen Smith have combined for 383 receiving yards and 4 touchdowns, while Le’Meke Brockington has 15 receptions.
The Minnesota Golden Gophers ground game is averaging 144 yards per contest, and Fame Ijeboi leads the way with 173 yards and 1 touchdown. Defensively, Minnesota is allowing 16.3 points and 230 yards per game. Devon Williams leads the Minnesota Golden Gophers with 31 tackles, Anthony Smith has 4.5 sacks and John Nestor has 2 interceptions.
Ohio State Buckeyes Betting Preview
The Ohio State Buckeyes beat Washington and Ohio, and they play Illinois next. The Ohio State Buckeyes have won 8 straight games. Julian Sayin is completing 78.8 percent of his passes for 987 yards, 10 touchdowns, and 3 interceptions. Jeremiah Smith and Carnell Tate have combined for 648 receiving yards and 7 touchdowns, while Max Klare has 6 receptions.
The Ohio State Buckeyes ground game is averaging 181.3 yards per contest, and Bo Jackson leads the way with 297 yards and 1 touchdown. Defensively, Ohio State is allowing 5.5 points and 229.3 yards per game. Arvell Reese leads the Ohio State Buckeyes with 25 tackles, Caden Curry has 5 sacks and Jermaine Mathews Jr. has 1 interception.
Minnesota Golden Gophers @ Ohio State Buckeyes Betting Trends: Week 6
Why the Ohio State Buckeyes will win
- Ohio State has won each of its last 26 October games at Ohio Stadium.
- Minnesota has lost eight of its last 10 October games against AP-ranked teams.
- Ohio State has covered the spread in seven of its last eight games as a favorite.
- Minnesota has failed to cover the spread in three of its last four games.
Why the Minnesota Golden Gophers will win
- Minnesota has won four of its last six October games as an underdog.
- Minnesota has covered the spread in each of its last four games against AP-ranked teams.
- Ohio State has failed to cover the spread in three of its last four October games as a favorite.
Total Points Facts
- Eight of Ohio State’s last nine games against conference opponents at Ohio Stadium have gone UNDER the total points line.
- Five of Minnesota’s last six games as an underdog against top-10 AP-ranked teams have gone OVER the total points line.
Ohio State Buckeyes Player Prop Facts
- Julian Sayin has recorded a 110.0+ passer rating in three consecutive games – equal-longest streak in the FBS.
Minnesota Golden Gophers Player Prop Facts
- Heading into Week 6, Jameson Geers leads Minnesota for touchdowns (2) this season.
Matchup/League Facts
- Ohio State ranks 1st among FBS teams for red zone percentage against this season (25.0).
- Ohio State ranks T2nd among FBS teams for H1 opponent points per game this season (1.5).
- Minnesota ranks 5th among FBS teams for rushing yards allowed per game this season (65.5).
- Minnesota ranks 9th among FBS teams for yards allowed per game this season (230.0).
Minnesota vs Ohio State Prediction
Minnesota is off to a decent start, but it hasn’t had the toughest schedule in the world up to this point, so the jury is still out to determine what’s real. Minnesota is hit or miss offensively, and I don’t trust the defense just yet against good teams. Ohio State has played elite football across the board and is 3-0-1 ATS on the season as well. We’ll learn more about Minnesota in this game. I trust Ohio State more up to this point. I’ll lay the points with the Buckeyes.