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Minnesota vs Ohio State Prediction 10/4/2025 Today’s College Football Picks

Ohio State Buckeyes running back Bo Jackson (25) runs over Washington Huskies linebacker Xe'ree Alexander (10) and defensive lineman Bryce Butler (92) during the NCAA football game at Husky Stadium in Seattle on Sept. 27, 2025. Ohio State won 24-6.

Ohio State Buckeyes running back Bo Jackson (25) runs over Washington Huskies linebacker Xe'ree Alexander (10) and defensive lineman Bryce Butler (92) during the NCAA football game at Husky Stadium in Seattle on Sept. 27, 2025. Ohio State won 24-6.

MATCHUP Minnesota Golden Gophers Ohio State Buckeyes
Team Records 3-2 5-0
Where Ohio Stadium, Columbus, OH
When Saturday, October 4, 2025
Time 07:30 PM EDT
TV NBC

The Minnesota Golden Gophers and Ohio State Buckeyes meet Saturday in college football action at Ohio Stadium. Here’s a Minnesota vs Ohio State Prediction. This article will include a Minnesota vs Ohio State Pick.

Minnesota Golden Gophers Betting Preview

The Minnesota Golden Gophers lost to Cal, beat Rutgers, and they play Purdue next. Minnesota has won 5 of its last 6 games. Drake Lindsey is completing 65.8 percent of his passes for 958 yards, 7 touchdowns, and 2 interceptions. Javon Tracy and Jalen Smith have combined for 383 receiving yards and 4 touchdowns, while Le’Meke Brockington has 15 receptions.

The Minnesota Golden Gophers ground game is averaging 144 yards per contest, and Fame Ijeboi leads the way with 173 yards and 1 touchdown. Defensively, Minnesota is allowing 16.3 points and 230 yards per game. Devon Williams leads the Minnesota Golden Gophers with 31 tackles, Anthony Smith has 4.5 sacks and John Nestor has 2 interceptions.

Ohio State Buckeyes Betting Preview

The Ohio State Buckeyes beat Washington and Ohio, and they play Illinois next. The Ohio State Buckeyes have won 8 straight games. Julian Sayin is completing 78.8 percent of his passes for 987 yards, 10 touchdowns, and 3 interceptions. Jeremiah Smith and Carnell Tate have combined for 648 receiving yards and 7 touchdowns, while Max Klare has 6 receptions.

The Ohio State Buckeyes ground game is averaging 181.3 yards per contest, and Bo Jackson leads the way with 297 yards and 1 touchdown. Defensively, Ohio State is allowing 5.5 points and 229.3 yards per game. Arvell Reese leads the Ohio State Buckeyes with 25 tackles, Caden Curry has 5 sacks and Jermaine Mathews Jr. has 1 interception.

Minnesota Golden Gophers @ Ohio State Buckeyes Betting Trends: Week 6

Why the Ohio State Buckeyes will win

Why the Minnesota Golden Gophers will win

Total Points Facts

Ohio State Buckeyes Player Prop Facts

Minnesota Golden Gophers Player Prop Facts

Matchup/League Facts

Minnesota vs Ohio State Prediction

Minnesota is off to a decent start, but it hasn’t had the toughest schedule in the world up to this point, so the jury is still out to determine what’s real. Minnesota is hit or miss offensively, and I don’t trust the defense just yet against good teams. Ohio State has played elite football across the board and is 3-0-1 ATS on the season as well. We’ll learn more about Minnesota in this game. I trust Ohio State more up to this point. I’ll lay the points with the Buckeyes.

Randy Chambers's Pick: Ohio State -24

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