Louisiana (1-2) vs Eastern Michigan (0-3)
September 20, 2025 at 03:30 PM EDT
The Line: Betting Odds: Eastern Michigan +2.5 — Over/Under: +50.5
The Louisiana-Lafayette Ragin’ Cajuns and Eastern Michigan Eagles meet Saturday in college football action at Rynearson Stadium. Here’s a Louisiana vs Eastern Michigan Prediction. This article will include a Louisiana vs Eastern Michigan Pick.
The Louisiana-Lafayette Ragin’ Cajuns beat McNeese, lost to Missouri, and they play Marshall next. The Louisiana-Lafayette Ragin’ Cajuns have lost 4 of their last 5 games. Daniel Beale is completing 41.7 percent of his passes for 91 yards, 1 touchdown, and 0 interceptions. Shelton Sampson Jr. and KeDarius Wade have combined for 88 receiving yards on 7 catches, while Caden Jensen has 5 receptions.
The Louisiana-Lafayette Ragin’ Cajuns ground game is averaging 194.3 yards per contest, and Zylan Perry leads the way with 226 yards and 1 touchdown. Defensively, Louisiana-Lafayette is allowing 25.3 points and 365 yards per game. Jaden Dugger leads the Louisiana-Lafayette Ragin’ Cajuns with 24 tackles, Jaelen Crider has 1 sack and Cameron Whitfield has 1 interception.
The Eastern Michigan Eagles lost to LIU and Kentucky, and they play Central Michigan next week. Eastern Michigan has lost 8 straight games. Noah Kim is completing 62.9 percent of his passes for 767 yards, 4 touchdowns, and 1 interception. Terry Lockett Jr. and Joshua Long have combined for 338 receiving yards and 2 touchdowns, while Dontae McMillan has 7 receptions.
The Eastern Michigan Eagles ground game is averaging 132 yards per contest, and Dontae McMillan leads the way with 219 yards and 1 touchdown. Defensively, Eastern Michigan is allowing 42.7 points and 525.7 yards per game. Marco Patierno leads the Eastern Michigan Eagles with 19 tackles, Messiah Blair has 1 sack and Joshua Scott has 2 pass deflections.
I’m not excited to lay chalk with Louisiana on the road, as the Ragin Cajuns have shown little offensively and can’t stop the run on defense. However, Eastern Michigan may be the worst defense in the country and has that stain of a loss to Long Island on its resume. It’s impossible to get behind Eastern Michigan with confidence. There’s much better games out there on a packed CFB Saturday card, but if forced to pick, I’m siding with Louisiana. Few teams have gotten off to a worse start than Eastern Michigan.
Louisiana-Lafayette Ragin’ Cajuns Betting Preview
The Louisiana-Lafayette Ragin’ Cajuns beat McNeese, lost to Missouri, and they play Marshall next. The Louisiana-Lafayette Ragin’ Cajuns have lost 4 of their last 5 games. Daniel Beale is completing 41.7 percent of his passes for 91 yards, 1 touchdown, and 0 interceptions. Shelton Sampson Jr. and KeDarius Wade have combined for 88 receiving yards on 7 catches, while Caden Jensen has 5 receptions.
The Louisiana-Lafayette Ragin’ Cajuns ground game is averaging 194.3 yards per contest, and Zylan Perry leads the way with 226 yards and 1 touchdown. Defensively, Louisiana-Lafayette is allowing 25.3 points and 365 yards per game. Jaden Dugger leads the Louisiana-Lafayette Ragin’ Cajuns with 24 tackles, Jaelen Crider has 1 sack and Cameron Whitfield has 1 interception.
Eastern Michigan Eagles Betting Preview
The Eastern Michigan Eagles lost to LIU and Kentucky, and they play Central Michigan next week. Eastern Michigan has lost 8 straight games. Noah Kim is completing 62.9 percent of his passes for 767 yards, 4 touchdowns, and 1 interception. Terry Lockett Jr. and Joshua Long have combined for 338 receiving yards and 2 touchdowns, while Dontae McMillan has 7 receptions.
The Eastern Michigan Eagles ground game is averaging 132 yards per contest, and Dontae McMillan leads the way with 219 yards and 1 touchdown. Defensively, Eastern Michigan is allowing 42.7 points and 525.7 yards per game. Marco Patierno leads the Eastern Michigan Eagles with 19 tackles, Messiah Blair has 1 sack and Joshua Scott has 2 pass deflections.
Louisiana Ragin’ Cajuns @ Eastern Michigan Eagles Betting Trends: Week 4
Why the Eastern Michigan Eagles will win
- Louisiana has lost three of its last four September games as a road favorite against non-AP-ranked teams.
- Eastern Michigan has won eight of its last 10 home games in September.
- Eastern Michigan has covered the spread in each of its last four September games as an underdog against non-AP-ranked teams.
- Louisiana has failed to cover the spread in five of its last six September games as a road favorite against non-AP-ranked teams.
Why the Louisiana Ragin’ Cajuns will win
- Eastern Michigan has lost each of its last eight games against non-AP-ranked teams.
- Louisiana has won 17 of its last 22 September games against non-AP-ranked teams.
- Eastern Michigan has failed to cover the spread in five of its last six games against non-AP-ranked teams.
- The favorite has covered the spread in three of Louisiana’s last four games.
Total Points Facts
- Six of Eastern Michigan’s last seven games as an underdog in Michigan have gone OVER the total points line.
- Five of Louisiana’s last six road games in September have gone OVER the total points line.
Eastern Michigan Eagles Player Prop Facts
- Heading into Week 4, Dontae McMillan leads the Mid-American Conference for yards per carry (7.3) this season.
Louisiana Ragin’ Cajuns Player Prop Facts
- Heading into Week 4, Elijah Davis leads Louisiana for touchdowns (2) this season.
Matchup/League Facts
- Eastern Michigan ranks 135th among FBS teams for points allowed per game this season (42.7).
- Eastern Michigan ranks 135th among FBS teams for yards allowed per game this season (525.7).
- Louisiana ranks 131st among FBS teams for yards per game this season (253.7).
- Louisiana ranks 130th among FBS teams for time of possession per game this season (24:46).
Louisiana vs Eastern Michigan Prediction
I’m not excited to lay chalk with Louisiana on the road, as the Ragin Cajuns have shown little offensively and can’t stop the run on defense. However, Eastern Michigan may be the worst defense in the country and has that stain of a loss to Long Island on its resume. It’s impossible to get behind Eastern Michigan with confidence. There’s much better games out there on a packed CFB Saturday card, but if forced to pick, I’m siding with Louisiana. Few teams have gotten off to a worse start than Eastern Michigan.