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Iowa vs Vanderbilt Prediction 12/31/2025 Today’s College Football Picks

Nov 28, 2025; Lincoln, Nebraska, USA; Iowa Hawkeyes kicker Drew Stevens (18) kicks a PAT against the Nebraska Cornhuskers during the fourth quarter at Memorial Stadium. Mandatory Credit: Dylan Widger-Imagn Images

Nov 28, 2025; Lincoln, Nebraska, USA; Iowa Hawkeyes kicker Drew Stevens (18) kicks a PAT against the Nebraska Cornhuskers during the fourth quarter at Memorial Stadium. Mandatory Credit: Dylan Widger-Imagn Images

MATCHUP Iowa Hawkeyes Vanderbilt Commodores
Team Records 8-4 10-2
Spread +5.5 -112 -5.5 -108
Moneyline +180 -218
Total Over 46.5 (-112) Under 46.5 (-108)
Where Raymond James Stadium, Tampa, FL
When Wednesday, December 31, 2025
Time 12:00 PM EST
TV ESPN
In this article, we will formulate an Iowa vs Vanderbilt Prediction for this College Football ReliaQuest Bowl Game on Wednesday, December 31st. Let’s take a look at the prediction for this College Football matchup.

Vanderbilt Commodores Preview


Vanderbilt has a 10-2 record this season and finished 6-2 in the SEC. They are coming off a 45-24 road win against Tennessee. Offensively, Vanderbilt averages 39.4 points per game, ranking 8th in the nation, while defensively, they allow 21.9 points per game, which is 35th. Vanderbilt averages 468.5 total yards per game (282.6 passing and 185.9 rushing), while allowing 355.8 total yards per game (103.3 rushing and 252.5 passing).

Diego Pavia leads Vanderbilt with 3,192 passing yards with 71.2% completed passes and 27 touchdowns. Diego Pavia leads the team in rushing yards with 826, while Eli Stowers has a team-high 62 receptions for 769 receiving yards. Defensively, Bryan Longwell has a team-high 68 total tackles (34 of them solo), while Miles Capers leads the team in sacks, with 4.5, and Martel Hight leads the team with 3 interceptions.

Iowa Hawkeyes Preview


Iowa has an 8-4 record this season and finished 6-3 in the Big Ten. They are coming off a 40-16 road win against Nebraska. Offensively, Iowa averages 28.9 points per game, ranking 58th in the nation, while defensively, they allow 15.2 points per game, which is 6th. Iowa averages 315.2 total yards per game (137.4 passing and 177.8 rushing), while allowing 270.6 total yards per game (112.4 rushing and 158.2 passing).

Mark Gronowski leads Iowa with 1,529 passing yards with 62.5% completed passes and 8 touchdowns. Kamari Moulton leads the team in rushing yards with 783, while DJ Vonnahme has a team-high 22 receptions for 288 receiving yards. Defensively, Karson Sharar has a team-high 78 total tackles (39 of them solo), while Ethan Hurkett, Max Llewellyn lead the team in sacks, with 6 each, and Zach Lutmer leads the team with 3 interceptions.

Iowa Hawkeyes @ Vanderbilt Commodores Betting Trends: Bowl


Why the Vanderbilt Commodores will win

Why the Iowa Hawkeyes will win

Total Points Facts

Vanderbilt Commodores Player Prop Facts

Iowa Hawkeyes Player Prop Facts

Matchup/League Facts

Iowa vs Vanderbilt Prediction


In this Iowa vs Vanderbilt Prediction, Vanderbilt is coming as -4-point favorites. Vanderbilt has been the better team this season, as it has just two defeats in 12 games played but both teams have a 3-2 away record, as this game takes place in a neutral site. Both teams are coming into this matchup in good form, as they are 5-1 and 5-2 in their last 6 and 7 games respectively. Iowa has a superior defense, allowing 6.7 points per game less than Vanderbilt, so I expect them to keep this one close. Take Iowa and the +4 points in this one.

Nikos Lagouretos's Pick: Iowa +4

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