Indiana vs Oregon Prediction 10/11/2025 Today’s College Football Picks

In this article, we will formulate an Indiana vs Oregon Prediction for this College Football Week 7 game on Saturday, October 11th at the Autzen Stadium. Let’s take a look at the prediction for this College Football matchup.

Oregon Ducks Preview

The Oregon Ducks have a 5-0 record this season and are sitting on the 3rd place of the Big Ten. They are 3-1-1 ATS, 3-2 in Over/Under and have a 2-0 away record and 3-0 home record. The Ducks are coming off a 30-24 away win against Penn State and are playing Rutgers and Wisconsin next.

Offensively, the Ducks average 46.6 points per game, which ranks 6th in the nation. Defensively, they allow 12.2 points per game, which is 8th. Oregon averages 503.8 total yards per game, with 239.4 rushing yards and 264.4 passing yards per game. They allow 238.2 total yards per game, with 114.8 rushing and 123.4 passing yards per game.

Dante Moore leads the Ducks with 1210 passing yards and 74.6% completed passes. Dierre Hill Jr leads the team in rushing yards, with 270, while Dakorien Moore has a team-high 19 caught passes for 296 receiving yards, and three touchdowns. Defensively, Bryce Boettcher has a team-high 40 total tackles, 10 of them solo. Matayo Uiagalelei leads the Ducks in sacks, with 4, while Teitum Tuioti has one interception.

Indiana Hoosiers Preview

The Indiana Hoosiers have a 5-0 record this season and are sitting on the 1st place of the Big Ten. They are 3-2 ATS, 3-2 in Over/Under and have a 1-0 away record and 4-0 home record. The Hoosiers are coming off a 20-15 away win against Iowa and are playing Michigan State and UCLA next.

Offensively, the Hoosiers average 47.8 points per game, which ranks 4th in the nation. Defensively, they allow 9.6 points per game, which is 3rd. Indiana averages 538.2 total yards per game, with 267.8 rushing yards and 270.4 passing yards per game. They allow 221.4 total yards per game, with 88 rushing and 133.4 passing yards per game.

Fernando Mendoza leads the Hoosiers with 1208 passing yards and 73% completed passes. Roman Hemby leads the team in rushing yards, with 351, while Elijah Sarratt has a team-high 31 caught passes for 412 receiving yards, and six touchdowns. Defensively, Louis Moore has a team-high 29 total tackles, 19 of them solo. Isaiah Jones leads the Hoosiers in sacks, with 3.5, while Louis Moore has three interceptions.

Indiana Hoosiers @ Oregon Ducks Betting Trends: Week 7

Why the Oregon Ducks will win

• Oregon has won each of its last 18 games at Autzen Stadium.
• Indiana has lost 19 of its last 20 road games against AP-ranked teams.
• Oregon has covered the spread in each of its last eight October games as a favorite against AP-ranked teams.
• Indiana has failed to cover the spread in seven of its last eight road games against AP-ranked teams.
• Oregon has won the first quarter in seven of its last eight games against conference opponents at Autzen Stadium.
• Oregon has won the first half in each of its last 11 games against conference opponents at Autzen Stadium.

Why the Indiana Hoosiers will win

• Indiana has won 10 of its last 11 games against conference opponents.
• Indiana has covered the spread in each of its last four games in October.
• Indiana has won the first quarter in eight of its last nine games against conference opponents.
• Indiana has won the first half in 10 of its last 12 games against conference opponents.

Total Points Facts

• Eleven of Indiana’s last 12 road games against conference opponents have gone OVER the total points line.
• Eight of Oregon’s last nine games as a favorite against AP-ranked teams have gone UNDER the total points line.

Oregon Ducks Player Prop Facts

• Dante Moore has thrown three or more touchdown passes in two consecutive games – equal-longest streak in the FBS.

Indiana Hoosiers Player Prop Facts

• Heading into Week 7, Fernando Mendoza ranks 1st amongst qualified players for passer rating (140.3) this season.

Matchup/League Facts

• Oregon has recorded the equal-most home wins by a margin of 15+ points of any FBS team this season (3).
• Oregon has recorded the equal-most home wins by a margin of 20+ points of any FBS team this season (3).
• Indiana has recorded the equal-most home wins by a margin of 10+ points of any FBS team this season (4).
• Indiana has recorded the equal-most home wins by a margin of 15+ points of any FBS team this season (3).

Indiana vs Oregon Prediction

In this Indiana vs Oregon Prediction, Oregon is coming as -7.5-point home favorites, with the total set at 55 points. Both teams have been outstanding this season and are undefeated in their five games played. Oregon has won and covered the spread in all three home games, while Indiana won but failed to cover their only road game. The Hoosiers are better both offensively and defensively, while the Ducks have the home court advantage, but still, this should be closer to a pickem. Expect a tight battle between two of the best teams in the nation, and take Indiana and the +7.5 points in this one.