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Indiana vs Oregon Prediction 10/11/2025 Today’s College Football Picks

Ohio State Buckeyes wide receiver Emeka Egbuka (2) catches a touchdown in front of Oregon Ducks defensive back Brandon Johnson (3) during the first half of the College Football Playoff quarterfinal at the Rose Bowl in Pasadena, Calif. on Jan. 1, 2025.

Ohio State Buckeyes wide receiver Emeka Egbuka (2) catches a touchdown in front of Oregon Ducks defensive back Brandon Johnson (3) during the first half of the College Football Playoff quarterfinal at the Rose Bowl in Pasadena, Calif. on Jan. 1, 2025.

MATCHUP Indiana Hoosiers Oregon Ducks
Team Records 6-0 5-1
Where Autzen Stadium, Eugene, OR
When Saturday, October 11, 2025
Time 03:30 PM EDT
TV CBS

In this article, we will formulate an Indiana vs Oregon Prediction for this College Football Week 7 game on Saturday, October 11th at the Autzen Stadium. Let’s take a look at the prediction for this College Football matchup.

Oregon Ducks Preview

The Oregon Ducks have a 5-0 record this season and are sitting on the 3rd place of the Big Ten. They are 3-1-1 ATS, 3-2 in Over/Under and have a 2-0 away record and 3-0 home record. The Ducks are coming off a 30-24 away win against Penn State and are playing Rutgers and Wisconsin next.

Offensively, the Ducks average 46.6 points per game, which ranks 6th in the nation. Defensively, they allow 12.2 points per game, which is 8th. Oregon averages 503.8 total yards per game, with 239.4 rushing yards and 264.4 passing yards per game. They allow 238.2 total yards per game, with 114.8 rushing and 123.4 passing yards per game.

Dante Moore leads the Ducks with 1210 passing yards and 74.6% completed passes. Dierre Hill Jr leads the team in rushing yards, with 270, while Dakorien Moore has a team-high 19 caught passes for 296 receiving yards, and three touchdowns. Defensively, Bryce Boettcher has a team-high 40 total tackles, 10 of them solo. Matayo Uiagalelei leads the Ducks in sacks, with 4, while Teitum Tuioti has one interception.

Indiana Hoosiers Preview

The Indiana Hoosiers have a 5-0 record this season and are sitting on the 1st place of the Big Ten. They are 3-2 ATS, 3-2 in Over/Under and have a 1-0 away record and 4-0 home record. The Hoosiers are coming off a 20-15 away win against Iowa and are playing Michigan State and UCLA next.

Offensively, the Hoosiers average 47.8 points per game, which ranks 4th in the nation. Defensively, they allow 9.6 points per game, which is 3rd. Indiana averages 538.2 total yards per game, with 267.8 rushing yards and 270.4 passing yards per game. They allow 221.4 total yards per game, with 88 rushing and 133.4 passing yards per game.

Fernando Mendoza leads the Hoosiers with 1208 passing yards and 73% completed passes. Roman Hemby leads the team in rushing yards, with 351, while Elijah Sarratt has a team-high 31 caught passes for 412 receiving yards, and six touchdowns. Defensively, Louis Moore has a team-high 29 total tackles, 19 of them solo. Isaiah Jones leads the Hoosiers in sacks, with 3.5, while Louis Moore has three interceptions.

Indiana Hoosiers @ Oregon Ducks Betting Trends: Week 7

Why the Oregon Ducks will win

Why the Indiana Hoosiers will win

Total Points Facts

Oregon Ducks Player Prop Facts

Indiana Hoosiers Player Prop Facts

Matchup/League Facts

Indiana vs Oregon Prediction

In this Indiana vs Oregon Prediction, Oregon is coming as -7.5-point home favorites, with the total set at 55 points. Both teams have been outstanding this season and are undefeated in their five games played. Oregon has won and covered the spread in all three home games, while Indiana won but failed to cover their only road game. The Hoosiers are better both offensively and defensively, while the Ducks have the home court advantage, but still, this should be closer to a pickem. Expect a tight battle between two of the best teams in the nation, and take Indiana and the +7.5 points in this one.

Nikos Lagouretos's Pick: Indiana +7.5

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