Houston (4-1) vs Oklahoma State (1-4)
October 11, 2025 at 12:00 PM EDT
The Line: Betting Odds: Oklahoma State +14 — Over/Under: +46.5
In this article, we will formulate a Houston vs Oklahoma State Prediction for this College Football Week 7 game on Saturday, October 11th at the Boone Pickens Stadium. Let’s take a look at the prediction for this College Football matchup.
Oklahoma State Cowboys Preview
The Oklahoma State Cowboys have a 1-4 record this season and are sitting on the 16th place of the Big 12. They are 1-4 ATS, 2-3 in Over/Under and have a 0-2 away record and 1-2 home record. The Cowboys are coming off a 13-41 away loss against Arizona and are playing Cincinnati and Texas Tech next.
Offensively, the Cowboys average 16.4 points per game, which ranks 130th in the nation. Defensively, they allow 36.2 points per game, which is 130th. Oklahoma State averages 315.8 total yards per game, with 140.4 rushing yards and 175.4 passing yards per game. They allow 474 total yards per game, with 179.4 rushing and 294.6 passing yards per game.
Zane Flores leads the Cowboys with 696 passing yards and 55.0% completed passes. Rodney Fields Jr. leads the team in rushing yards, with 213, while Sam Jackson has a team-high 12 caught passes for 149 receiving yards. Defensively, Bryan McCoy has a team-high 39 total tackles, 15 of them solo. Wendell Gregory leads the Cowboys in sacks, with 3, while Kale Smith has one interception.
Houston Cougars Preview
The Houston Cougars have a 4-1 record this season and are sitting on the 5th place of the Big 12. They are 3-2 ATS, 3-2 in Over/Under and have a 2-0 away record and 2-1 home record. The Cougars are coming off a 11-35 home loss against Texas Tech and are playing Arizona and Arizona State next.
Offensively, the Cougars average 27.2 points per game, which ranks 80th in the nation. Defensively, they allow 17.6 points per game, which is 29th. Houston averages 357.0 total yards per game, with 157.8 rushing yards and 199.2 passing yards per game. They allow 322.8 total yards per game, with 141.6 rushing and 181.2 passing yards per game.
Conner Weigman leads the Cougars with 910 passing yards and 59.3% completed passes. Dean Connors leads the team in rushing yards, with 355, while Stephon Johnson Jr. has a team-high 10 caught passes for 261 receiving yards, and 2 touchdowns. Defensively, Carlos Allen has a team-high 36 total tackles, 14 of them solo. Corey Platt Jr. leads the Cougars in sacks, with 2.5, while Latrell McCutchin has one interception.
Houston Cougars @ Oklahoma State Cowboys Betting Trends: Week 7
Why the Oklahoma State Cowboys will win
- Oklahoma State has won each of its last five October games as a home underdog.
- Houston has lost five of its last six road games against conference opponents.
- Oklahoma State has covered the spread in each of its last five October games as a home underdog.
- Houston has failed to cover the spread in three of its last four road games against non-AP-ranked teams.
- Houston has lost the first half in five of its last six games against conference opponents.
Why the Houston Cougars will win
- Oklahoma State has lost each of its last 12 games against conference opponents.
- Houston has won each of its last 11 October games as a favorite.
- Oklahoma State has failed to cover the spread in nine of its last 10 games.
- Houston has covered the spread in each of its last four games in Oklahoma.
- Oklahoma State has lost the first half in each of its last six games against conference opponents.
Total Points Facts
- Each of Oklahoma State’s last six games as a home underdog against teams from Texas have gone OVER the total points line.
- Each of Houston’s last five games as a road favorite have gone OVER the total points line.
Oklahoma State Cowboys Player Prop Facts
- Heading into Week 7, Zane Flores has the most pass attempts without a passing touchdown this season (140).
Houston Cougars Player Prop Facts
- Heading into Week 7, Stephon Johnson leads the Big 12 Conference for yards per reception (26.1) this season.
Matchup/League Facts
- Oklahoma State ranks 134th among FBS teams for H1 opponent points per game this season (23.2).
- Oklahoma State ranks T134th among FBS teams for average point differential in third quarters this season (-8.4).
- Houston ranks T6th among FBS teams for Q3 opponent points per game this season (1.2).
- Houston ranks T6th among FBS teams for 4th down conversion percentage against this season (22.2).
Houston vs Oklahoma State Prediction
In their previous meeting in 2023, Oklahoma State won 43-30 on the road. Both teams are tied 2-2 in their four meetings, and are 1-1 in Oklahoma. All of their four meetings have gone over the total.
In this Houston vs Oklahoma State Prediction, Houston is coming as -14.5-point road favorites, with the total set at 47.5 points. Both teams are in opposite trajectories this season, with the Cowboys having won only once, and the Cougars having lost only once. Houston has won both of its road games, and are superior both offensively and defensively, winning by an average of 9.6 points per game. On the flip side, Oklahoma State has been losing by an average of 19.8 points per game, and are a bottom-7 team in the nation both offensively and defensively. Take Houston and lay the -14 points for an easy road win.