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Eastern Michigan vs Kentucky Prediction 9/13/2025 Today’s College Football Picks

Sep 6, 2025; Lexington, Kentucky, USA; Kentucky Wildcats quarterback Zach Calzada (5) warms up before the game against the Mississippi Rebels at Kroger Field. Mandatory Credit: Jordan Prather-Imagn Images

Sep 6, 2025; Lexington, Kentucky, USA; Kentucky Wildcats quarterback Zach Calzada (5) warms up before the game against the Mississippi Rebels at Kroger Field. Mandatory Credit: Jordan Prather-Imagn Images

Eastern Michigan (0-2) vs Kentucky (1-1)

September 13, 2025 at 07:30 PM EDT

The Line: Betting Odds: Kentucky -24.5 — Over/Under: +47.5

(Get latest betting odds)

The Eastern Michigan Eagles and the Kentucky Wildcats meet in week 3 college football action from Kroger Field on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Eastern Michigan Eagles vs. Kentucky Wildcats prediction.

Eastern Michigan Eagles Recap

The Eastern Michigan Eagles come into this game looking to rebound from a 28-23 loss at the hands of LIU last time out to sit at 0-2 on the year. After this game, the Eagles will head home for a game against Louisiana.

Eagles Still Looking For First Win

Noah Kim has thrown for 437 yards and 3 touchdowns on 65.1% passing while Dontae McMillan has 136 rushing yards and a touchdown. Terry Lockett Jr. leads EMU’s receiving group with 13 catches for 140 yards as well this season. On defense, Marco Patierno and Bryce Llewellyn each have a team-high 12 total tackles while Messiah Blair has the lone sack for Eastern Michigan defensively this season.

Kentucky Wildcats Recap

The Kentucky Wildcats come into this game looking to bounce back from their 30-23 loss at the hands of Ole Miss last time out to sit at 1-1 this season. After this game, Kentucky will have a bye before heading on the road for a game against South Carolina.

Kentucky Looking To Avoid Trap Spot

Zach Calzada’s thrown for 234 yards and an interception on 47.2% passing while Dante Dowdell’s rushed for 185 yards and a touchdown to lead Kentucky on the ground and Seth McGowan has 171 rushing yards and 3 touchdowns as well this season. Ja’Mori Maclin leads Kentucky’s receiving group with 67 receiving yards while Kendrick Law has a team-high 6 receptions so far this year. On defense, Alex Afari Jr. has a team-high 23 total tackles including 16 solo tackles while Ty Bryant has a pair of interceptions and Steven Soles Jr. has a pair of sacks so far this season.

Eastern Michigan Eagles vs. Kentucky Wildcats Prediction

I’m on the under in this one. I get the case to be made for either side here, but EMU just got beat up by a subpar LIU squad, and I’m not fond of this Kentucky team with Calzada at QB. I just think you have two teams in a matchup where I don’t anticipate a ton of points, so give me the under here.

Chris Ruffolo's Pick: Under 47.5

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