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East Carolina vs UTSA Prediction 11/22/2025 Today’s College Football Picks

Sep 14, 2024; Austin, Texas, USA; Texas Longhorns defensive back Warren Roberson (24) tackles Texas Roadrunners wide receiver Devin McCuin (3) during the second half at Darrell K Royal-Texas Memorial Stadium. Mandatory Credit: Scott Wachter-Imagn Images

Sep 14, 2024; Austin, Texas, USA; Texas Longhorns defensive back Warren Roberson (24) tackles Texas Roadrunners wide receiver Devin McCuin (3) during the second half at Darrell K Royal-Texas Memorial Stadium. Mandatory Credit: Scott Wachter-Imagn Images

MATCHUP East Carolina Pirates UTSA Roadrunners
Team Records 7-3 5-5
Spread -2.5 -110 +2.5 -110
Moneyline -130 +110
Total Over 62.5 (-110) Under 62.5 (-110)
Where Alamodome, San Antonio, TX
When Saturday, November 22, 2025
Time 03:30 PM EST
TV ESPN+
The East Carolina Pirates and UTSA Roadrunners meet Saturday in college football action at Alamodome. Here’s a East Carolina vs UTSA Prediction. This article will include a East Carolina vs UTSA Pick.

East Carolina Pirates Betting Preview


The East Carolina Pirates beat Charlotte and Memphis, and they play FAU next. East Carolina has won 4 straight games. Katin Houser is completing 66.6 percent of his passes for 2,801 yards, 15 touchdowns, and 5 interceptions. Anthony Smith and Yannick Smith have combined for 1,328 receiving yards and 9 touchdowns, while Brock Spalding has 35 receptions.

The East Carolina Pirates ground game is averaging 179.6 yards per contest, and London Montgomery leads the way with 637 yards and 7 touchdowns. Defensively, East Carolina is allowing 18.3 points and 339.1 yards per game. Ja’Marley Riddle leads the East Carolina Pirates with 58 tackles, Zion Wilson has 5 sacks and Teagan Wilk has 1 interception.

UTSA Roadrunners Betting Preview


The UTSA Roadrunners lost to USF, beat Charlotte, and play Army next. UTSA has split its last 10 games. Owen McCown is completing 67.3 percent of his passes for 2,186 yards, 20 touchdowns, and 6 interceptions. Devin McCuin and AJ Wilson have combined for 1,015 receiving yards and 10 touchdowns, while David Amador II has 35 receptions.

The UTSA Roadrunners ground game is averaging 171.3 yards per contest, and Robert Henry Jr. leads the way with 983 yards and 9 touchdowns. Defensively, UTSA is allowing 30.4 points and 388.1 yards per game. Shad Banks Jr. leads the UTSA Roadrunners with 64 tackles, Nnanna Anyanwu has 5 sacks and Tyan Milton has 2 interceptions.

Why the UTSA Roadrunners will win

Why the East Carolina Pirates will win

Total Points Facts

UTSA Roadrunners Player Prop Facts

East Carolina Pirates Player Prop Facts

Matchup/League Facts

East Carolina vs UTSA Prediction


UTSA is at home and needs one more win to clinch a bowl berth, so I can understand why oddsmakers are showing them some love. However, this line is soft. East Carolina is simply the better team playing the better football. East Carolina has a top-20 total offense and should have a field day against a UTSA squad that’s 112th in scoring defense. UTSA is 4-8 ATS in its last 12 games as an underdog. I’m not getting enough points to step in front of an ECU squad playing its best ball of the season. Give me East Carolina and the small number.

Randy Chambers's Pick: East Carolina -2.5

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