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Charlotte vs Ole Miss Prediction 9/12/2026 Today’s College Football Picks

Sep 6, 2026; Nashville, Tennessee, USA;  Mississippi Rebels running back Kewan Lacy (5) carries the ball for a touchdown against the Louisville Cardinals during the second quarter at Nissan Stadium.  Mandatory Credit: Steve Roberts-Imagn Images

Sep 6, 2026; Nashville, Tennessee, USA; Mississippi Rebels running back Kewan Lacy (5) carries the ball for a touchdown against the Louisville Cardinals during the second quarter at Nissan Stadium. Mandatory Credit: Steve Roberts-Imagn Images

MATCHUP Charlotte 49ers Ole Miss Rebels
Team Records 0-1 1-0
Where Vaught-Hemingway Stadium, Oxford, MS
When Saturday, September 12, 2026
Time 07:45 PM EDT
TV ESPN2
The Charlotte 49ers and Ole Miss Rebels meet Saturday in week 2 college football action at Vaught-Hemingway Stadium. Here’s a Charlotte vs Ole Miss Prediction. This article will include a Charlotte vs Ole Miss Pick.

Charlotte 49ers Betting Preview


The Charlotte 49ers lost to The Citadel and play App State next. Charlotte has lost 10 straight games. Cole Gonzales is completing 68.3 percent of his passes for 322 yards, 3 touchdowns, and 2 interceptions. Jaylen Hampton and Jaden Barnes have combined for 210 receiving yards and 2 touchdowns, while Derrick Eley has 4 receptions.

The Charlotte 49ers ground game is averaging 216 yards per contest, and Khamani Alexander leads the way with 138 yards and 1 touchdown. Defensively, Charlotte is allowing 43 points and 400 yards per game. Collin Gill leads the Charlotte 49ers with 11 tackles, Caleb Irving has 1 sack, and Jerry Wall III has 1 sack.

Ole Miss Rebels Betting Preview


The Ole Miss Rebels beat Louisville, and they play LSU next. The Ole Miss Rebels look to start 2-0 for a sixth straight season. Trinidad Chambliss is completing 58.3 percent of his passes for 336 yards, 3 touchdowns, and 1 interception. Deuce Alexander and Caleb Odom have combined for 225 receiving yards and 3 touchdowns, while Horatio Fields has 5 receptions.

The Ole Miss Rebels’ ground game is averaging 152 yards per contest, and Kewan Lacy leads the way with 61 yards and 1 touchdown. Defensively, Ole Miss is allowing 38 points and 469 yards per game. Jaylon Braxton leads the Ole Miss Rebels with 8 tackles, Luke Ferrelli has 1 sack, and Tah’j Butler has 1 pass deflection.

Why the Ole Miss Rebels will win

Why the Charlotte 49ers will win

Total Points Facts

Ole Miss Rebels Player Prop Facts

Charlotte 49ers Player Prop Facts

Matchup/League Facts

Charlotte vs Ole Miss Prediction


Charlotte going to three overtimes against The Citadel isn’t encouraging heading into this spot. Ole Miss is capable of laying the wood here. However, this is a sandwich spot for Ole Miss after a game against Louisville and with LSU on deck. It will be interesting to see if Ole Miss can refocus after a last-second win. Lacy is also banged up for Ole Miss. A lot of points here. I’ll take a shot with Charlotte and the endless free touchdowns.

Randy Chambers's Pick: Charlotte +45.5

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