Buffalo vs Central Michigan Prediction 11/12/2025 Today’s College Football Picks
Chris Ruffolo
Aug 28, 2025; Minneapolis, Minnesota, USA; Buffalo Bulls quarterback Ta'Quan Roberson (2) looks to throw against the Minnesota Golden Gophers during the first half of the game at Huntington Bank Stadium. Mandatory Credit: Matt Krohn-Imagn Images
MATCHUP
Bulls Buffalo
Chippewas Central Michigan
Team Records
5-4
5-4
Spread
+1.5 -115
-1.5 -105
Moneyline
+102
-122
Total
Over 44.5 (-105)
Under 44.5 (-115)
Where
Kelly/Shorts Stadium, Mount Pleasant, MI
When
Wednesday, November 12, 2025
Time
07:00 PM EST
TV
CBSSN
The Buffalo Bulls and the Central Michigan Chippewas meet in week 12 college football action from Kelly/Shorts Stadium on Wednesday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Buffalo Bulls vs. Central Michigan Chippewas prediction.
Buffalo Bulls Recap
The Buffalo Bulls come into this game looking to build on a 28-3 win over Bowling Green last time out to improve to 5-4 this season. After this game, Buffalo will head home for a game against Miami-Ohio.
Bulls Win 3 Of Last 4
Ta’Quan Roberson has thrown for 1,739 yards, 12 touchdowns and 8 interceptions on 60.5% passing while Gunnar Gray has thrown for 174 yards, a touchdown and an interception on 52.3% passing while Al-Jay Henderson has rushed for 663 yards and 5 touchdowns and Lamar Sperling has 202 rushing yards and a TD as well. Nik McMillan has a team-high 590 receiving yards coming on 42 catches with a touchdown while Victor Snow has 586 receiving yards with 7 TDs and a team-high 45 catches. Jasaiah Gathings has 274 receiving yards and a touchdown as well for the Bulls. On defense, Red Murdock has a team-high 105 total tackles and 4.5 sacks while Junior Poyser also has a team-high 4.5 sacks. As a unit, Buffalo’s defense has combined for 33 sacks and 4 interceptions so far this season.
Central Michigan Chippewas Recap
The Central Michigan Chippewas come into this game looking to bounce back from a 24-21 loss at the hands of Western Michigan last time out to sit at 5-4 this season. After this game, Central Michigan will head on the road for a game against Kent State.
Chippewas Have Two-Game Win Streak Snapped
Joe Labas has thrown for 1,066 yards, 8 touchdowns and 2 interceptions on 71.6% passing while Angel Flores leads the Chippewas in rushing with 519 yards and 8 TDs and Nahree Biggins have 426 rushing yards and 2 TDs. Trey Cornist has 299 rushing yards and a TD and Brock Townsend has 288 rushing yards with 2 TDs as well. Langston Lewis has 21 catches for 295 yards and 2 TDs while Tommy McIntosh has 225 receiving yards. Three more Chippewas have 100+ receiving yards as well on the year. On defense, Jordan Kwiatkowski has a team-high 70 total tackles and a pair of interceptions while Michael Heidman has a team-high 5.5 sacks as well this season. As a unit, Central Michigan’s defense has combined for 16 sacks and 10 interceptions so far this season.
Buffalo Bulls @ Central Michigan Chippewas Betting Trends: Week 12
Why the Central Michigan Chippewas will win
Central Michigan has won each of its last nine games as a home favorite.
Central Michigan has covered the spread in each of its last six home games.
Buffalo has failed to cover the spread in six of its last seven games.
Central Michigan has won the first quarter in four of its last five games against conference opponents.
Central Michigan has won the first half in four of its last five games against conference opponents.
Why the Buffalo Bulls will win
Buffalo has won each of its last three November games as an underdog.
Central Michigan has lost nine of its last 10 games in November.
Buffalo has covered the spread in each of its last four games as a road underdog.
Buffalo has won the first quarter in four of its last five road games against conference opponents.
Total Points Facts
Each of Central Michigan’s last five home games against teams from New York have gone OVER the total points line.
Six of Buffalo’s last seven games in Michigan have gone OVER the total points line.
Central Michigan Chippewas Player Prop Facts
Heading into Week 12, Angel Flores ranks T2nd in the Mid-American Conference for rushing touchdowns (8) this season.
Buffalo Bulls Player Prop Facts
Heading into Week 12, Nik McMillan is one of only three players in the FBS to record 100+ receiving yards in three or more consecutive games this season.
Matchup/League Facts
Central Michigan ranks 135th among FBS teams for Q4 points per game this season (2.4).
Central Michigan ranks 127th among FBS teams for H2 points per game this season (7.8).
Buffalo ranks 5th among FBS teams for Q1 opponent points per game this season (1.9).
Buffalo ranks 9th among FBS teams for H1 opponent points per game this season (6.9).
Buffalo Bulls vs. Central Michigan Chippewas Prediction
I’m on Central Michigan here. I could easily make the case that Buffalo could be winless in MAC play if they didn’t get a couple of bounces, and I’ve sold my stock on this Buffalo team as I’m simply not a believer. Central Michigan is still a solid squad, especially at home, and I think they get the win at home here. Give me Central Michigan in this one.
