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Arizona vs Houston Prediction 10/18/2025 Today’s College Football Picks

Sep 27, 2025; Ames, Iowa, USA; Arizona Wildcats quarterback Noah Fifita (1) looks to pass against the Iowa State Cyclones during the first half at Jack Trice Stadium. Mandatory Credit: Reese Strickland-Imagn Images

Sep 27, 2025; Ames, Iowa, USA; Arizona Wildcats quarterback Noah Fifita (1) looks to pass against the Iowa State Cyclones during the first half at Jack Trice Stadium. Mandatory Credit: Reese Strickland-Imagn Images

MATCHUP Arizona Wildcats Houston Cougars
Team Records 4-3 6-1
Where TDECU Stadium, Houston, TX
When Saturday, October 18, 2025
Time 12:00 PM EDT
TV FS1

The Arizona Wildcats and the Houston Cougars meet in week 8 college football action from TDECU Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Arizona Wildcats vs. Houston Cougars prediction.

Arizona Wildcats Recap

The Arizona Wildcats come into this game looking to bounce back from their 33-27 loss at the hands of BYU in their last game to sit at 4-2 this season. After this game, Arizona will have a bye week before a road game against Colorado.

Wildcats Alternate Wins & Losses In 4 Straight

Noah Fifita has thrown for 1,560 yards, 15 touchdowns and 4 interceptions so far this season while Ismail Mahdi has a team-high 403 rushing yards and a touchdown so far this season. Quincy Craig also has 207 rushing yards while Javin Whatley has a team-high 25 catches for 328 yards and 3 touchdowns to lead Arizona in receiving. Kris Hutson has 20 catches for 262 receiving yards and 2 TDs while Chris Hunter has 17 grabs for 239 yards and 2 TDs and Luke Wysong has 220 receiving yards so far this season. On defense, Dalton Johnson has a team-high 41 total tackles including 21 solo tackles while Riley Wilson has a team-high 3 sacks so far this year. As a unit, the Arizona defense as a whole has combined for 14 sacks and 9 interceptions so far this season.

Houston Cougars Recap

The Houston Cougars come into this game looking to build on a 39-17 win over Oklahoma State last time out to improve to 5-1 so far this season. After this game, Houston will head on the road for a game against Arizona State.

Cougars Looking To Clinch Bowl Eligibility

Connor Weigman has thrown for 1,216 yards, 8 touchdowns and 2 interceptions on 61.5% passing while Dean Connors has rushed for 438 yards and 4 TDs on the ground this season. Weigman and Stacy Sneed each have 100+ rushing yards as well with Weigman adding 5 rushing TDs. Amare Thomas leads the Cougars with 441 receiving yards and 2 touchdowns while Stephon Johnson has 275 receiving yards and 2 TDs and Tanner Koziol has 310 receiving yards and a pair of scores as well this season. On defense, Jalen Garner has a team-high 42 total tackles while Corey Platt Jr. has a team-high 2.5 sacks. As a unit, Houston’s defense has combined for 13 sacks and 6 interceptions so far this season.

Arizona Wildcats @ Houston Cougars Betting Trends: Week 8

Why the Houston Cougars will win

Why the Arizona Wildcats will win

Total Points Facts

Houston Cougars Player Prop Facts

Arizona Wildcats Player Prop Facts

Matchup/League Facts

Arizona Wildcats vs. Houston Cougars Prediction

I’m leaning towards Arizona here. I just think that Houston is slightly overrated and are not the best 5-1 team I’ve seen in my years of watching football. I think this are two really solid defenses, but I trust Arizona to do more offensively than I do Houston in this one so give me Arizona on the road in this one.

Chris Ruffolo's Pick: Arizona -1.5

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