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Arizona State vs Mississippi State Prediction 9/6/2025 Today’s College Football Picks

Mississippi State's running back Davon Booth (21) celebrates a touchdown during the Egg Bowl game against Mississippi at Vaught-Hemingway Stadium on Friday, Nov. 29, 2024.

Mississippi State's running back Davon Booth (21) celebrates a touchdown during the Egg Bowl game against Mississippi at Vaught-Hemingway Stadium on Friday, Nov. 29, 2024.

Arizona State (1-0) vs Mississippi State (1-0)

September 6, 2025 at 07:30 PM EDT

The Line: Betting Odds: Mississippi State +7 — Over/Under: +58.5

(Get latest betting odds)

The Arizona State Sun Devils and Mississippi State Bulldogs meet Saturday in college football action at Davis Wade Stadium. Here’s a Arizona State vs Mississippi State Prediction. This article will include a Arizona State vs Mississippi State Pick.

Arizona State Sun Devils Betting Preview


The Arizona State Sun Devils beat Northern Arizona, and they play Texas State and Baylor next. Arizona State has won 7 straight regular season games. Sam Leavitt is completing 64.1 percent of his passes for 257 yards, 2 touchdowns, and 1 interception. Jordan Tyson and Kyson Brown have combined for 213 receiving yards and 2 touchdowns, while Chamon Metayer has 1 reception.

The Arizona State Sun Devils ground game is averaging 201 yards per contest, and Kyson Brown leads the way with 73 yards on 7 carries. Defensively, Arizona State is allowing 19 points and 331 yards per game. Jordan Crook leads the Arizona State Sun Devils with 7 tackles, Keith Abney II has 1 sack and Montana Warren has 2 pass deflections.

Mississippi State Bulldogs Betting Preview


The Mississippi State Bulldogs beat Southern Miss, and they play Alcorn State and Northern Illinois next. Mississippi State hasn’t won two straight games since October 2023. Blake Shapen is completing 76.5 percent of his passes for 270 yards, 1 touchdown, and 1 interception. Brenen Thompson and Seydou Traore have combined for 169 receiving yards and 1 touchdown, while Anthony Evans III has 4 receptions.

The Mississippi State Bulldogs ground game is averaging 188 yards per contest, and Davon Booth leads the way with 79 yards and 1 touchdown. Defensively, Mississippi State is allowing 17 points and 301 yards per game. Jalen Smith leads the Mississippi State Bulldogs with 7 tackles, Will Whitson has 1 sack and Brylan Lanier has 1 interception.

Arizona State vs Mississippi State Prediction

Mississippi State has some showing and proving to do after last season, and a win over Southern Miss doesn’t move the needle. If anything, Mississippi State wasn’t all that impressive in that opening victory. This is one of the more talented Arizona State teams we’ve seen in a while, and the Sun Devils have covered eight of their last 10 games. Mississippi State is 7-12-1 ATS in its last 20 games as an underdog. Mississippi State will be energized for this contest, but I don’t trust the defense and I don’t believe there’s enough offensive horsepower to counter ASU. Could be competitive for a half, but I like Arizona State to pull away, snagging a double-digit victory.

Randy Chambers's Pick: Arizona State -7

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