Louisville vs Pittsburgh Prediction - College Football Picks 10/14/23

Pittsburgh Panthers (1-4) vs Louisville Cardinals (6-0)

Game Info: Saturday, October 14, 2023 at 6:30 pm (Acrisure Stadium)

Betting Odds: Pittsburgh Panthers +7.5 -- Over/Under: 44.5 Click Here for the Latest Odds

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The Louisville Cardinals will play the Pittsburgh Panthers in an ACC game on Saturday night at Acrisure Stadium in Pittsburgh, Pennsylvania. Louisville is coming off of a huge home win against Notre Dame, while Pittsburgh has lost four games in a row. 

Louisville Preview

The Louisville Cardinals are 6-0 (3-0) this season after they defeated Notre Dame by a score of 33-20 in their last game. Louisville was tied at 7 going into halftime, but they fell behind quickly in the third quarter after a Notre Dame field goal. The Cardinals were able to score 26 of the next 29 points to pull away for the win. The Cardinals out gained ND by a total of 330-298 and forced five turnovers in the game. Louisville also has wins over Georgia Tech, Murray State, Indiana, Boston College, and NC State. The Louisville offense is scoring 36.3 points per game with 275 passing yards per game and 192.3 rushing yards per game, while going 39.7% on third downs. Jack Plummer has thrown for 1,551 yards, 12 touchdowns, and six interceptions for the Cardinals this year. Jawhar Jordan has rushed for 653 yards and eight scores, while Jamari Thrash has caught 30 passes for 519 yards and six touchdowns. The Louisville defense is allowing 17.7 points against per game this season.

Pittsburgh Preview

The Pittsburgh Panthers are 1-4 (0-2) this season after they lost to Virginia Tech by a score of 38-21 in their last game. Pittsburgh was tied at seven at the end of the first quarter, but they allowed the next 21 points, which allowed Virginia Tech to pull away. The Panthers were out gained by a total of 427-273 and went 2-10 on third downs in the loss. Pittsburgh won their season opener against Wofford, but has lost the last four games to Cincinnati, West Virginia, North Carolina, and Virginia Tech. The Pittsburgh offense is scoring 23.4 points per game with 192.6 passing yards and 116.2 rushing yards per game, while going 37.7% on third down attempts this year. Christian Veilleux will be the starting quarterback going forward and he has thrown for 145 yards, one touchdown, and two interceptions this year. Rodney Hammond Jr. has rushed for 196 yards and three touchdowns, while Gavin Bartholomew has caught 12 passes for 258 yards and one score. The Pittsburgh defense is giving up 26 points against per game and has allowed 79 points in their last two games. 

Pittsburgh Panthers Team Facts

  • Pittsburgh has won each of its last four matches when playing with a rest advantage.
  • Pittsburgh has failed to cover the spread in seven of its last eight games as an underdog.
  • Pittsburgh has won the first half in six of its last seven games against conference opponents at Acrisure Stadium.
  • Seven of Pittsburgh's last eight games at Acrisure Stadium have gone OVER the total points line.

Louisville Cardinals Team Facts

  • Louisville has won each of its last nine games as a favorite.
  • The team ranked 14th in the AP Poll has covered the spread in eight of its last nine games.
  • Nine of Louisville's last 11 games have gone UNDER the total points line.


Pittsburgh comes into this game needing a win to snap their four game losing streak, while Louisville is starting to look like one of the better teams in the country. The Cardinals are undefeated and gave Notre Dame a ton of problems last weekend. Pittsburgh has allowed a lot of points in three of their last four games and I see another tough matchup here. I think Louisville is going to move the ball with ease, but I also think Pittsburgh will score a few times. Give me the over here. 

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

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