USC at Arizona - 10/29/22 College Football Picks and Prediction

Arizona Wildcats (3-4) vs USC Trojans (6-1)

Game Info: Saturday, October 29, 2022 at 7:00 pm (Arizona Stadium)

Betting Odds: Arizona Wildcats +15.5 -- Over/Under: 76.5 Click Here for the Latest Odds

Where to Watch: Pac-12 Network Stream live sports and exclusive originals on ESPN+. Sign up now! Advertisement

The USC Trojans and Arizona Wildcats face off on Saturday in a Pac-12 college football showdown at Arizona Stadium. When these two teams faced off in 2021 it was USC that secured the 41-34 victory. 

USC comes into this game with a 6-1 record overall but their one loss came in the last game. Utah outscored USC 15-7 in the 4th quarter, and that led to the one-point defeat. USC’s offense scored 42 points and they were led by Caleb Williams who completed 25 of his 42 passes for 381 yards, five touchdowns, and zero interceptions. USC is averaging 40.4 points while their defense is giving up 22.1 points per game. The offense is ranked 21st in the league, and they are going to need the offense to be strong again here. 

On the other side of this matchup is Arizona who sits with a 3-4 record overall and they have gone 4-3 against the spread. In the last game against Washington, Arizona scored 39 points but the defense gave up 49 points, and that led to the defeat. Two games ago against Oregon, Arizona really struggled and they were defeated 49-22. In the last game against Jayden de Laura, he completed 25 of his 34 passes for 400 yards and four touchdowns. Arizona is averaging 31.6 points while their defense is giving up 36.3 points per game. 

USC is 5-1 against the spread in their last six games on grass. Arizona is 5-2 against the spread in their last seven home games. The underdog is 12-5 against the spread in the last 17 meetings played between the two teams. The under is 6-2 in the last eight meetings played between USC and Arizona. 

Two games ago Arizona gave up 49 points to Oregon and they are going to really struggle against this USC offense. Williams threw for five touchdowns in the last game and he is going to have no issue moving the ball against this Arizona defense. Williams might not throw the five touchdowns again, but this game is going to be a blowout. Back USC to cover the spread.

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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