Southern Miss at Alabama 9/25/21 College Football Picks and Predictions

Southern Miss at Alabama 9/25/21 College Football Picks and Predictions Photo by Butch Dill-USA TODAY Sports

Alabama Crimson Tide (3-0) vs Southern Miss Golden Eagles (1-2)

Game Info: Saturday, September 25, 2021 at 7:30 pm (Bryant-Denny Stadium)

Betting Odds: Alabama Crimson Tide -45.5 -- Over/Under: 58.5 Click Here for the Latest Odds

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Southern Miss faces Alabama on Saturday, September 25th, at Bryant-Denny Stadium for a Week 4 college football matchup. 

Southern Miss is 1-2 to start the season and its last game was in Week 3 against Troy. Troy got the better of South Miss in a 21-9 contest and Southern Miss is now 0-2 against FBS opponents this season. Southern Miss will be 0-3 by a very comfortable margin against the FBS after it completes this game with Alabama, the nation's #1 ranked team and a team that has not lost a game since 2019. Southern Miss's offense has struggled this season, only scoring 18 points per game and earning only 284 total yards per contest as well. This makes Southern Miss one of the weaker offensive units in the FBS, but the defense has been a completely different story. Southern Miss has been fantastic against opposing ground games, only allowing an average of 1.4 yards per carry and 51 total rushing yards or fewer in each of its three games. Southern Miss has also forced 9 sacks this season including four last week against Troy. 

Alabama was able to squeak by in the Swamp in last week's contest with Florida. Alabama defeated the Gators by a final score of 31-29 in a game that went down to the wire. Alabama is now a perfect 3-0 on the year and will be 4-0 after this week as it gets ready for more SEC action. Alabama has scored 41 points per game this season and has earned 416 total yards per game as well. Alabama's defense has held its opponents to 19 points per game and only 307 total yards per contest as well. Alabama has not been nearly as dominant as it was in 2020, but there is no doubt that Alabama is deserving of that #1 ranking so far this season. Alabama will look to keep everyone healthy in what should be a feel-good game in front of the home crowd. 

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Alabama is a whopping 45.5-point favorite and the total is set at 58.5. I cannot see Southern Miss scoring more than a field goal or two in this game, as the offense has been miserable and the offensive line has allowed 16 sacks already this season (nine last week). Alabama will be able to score easily but Southern Miss' run defense could make things a bit difficult early on. I think we see this game go under the total, as I think all of the offense comes from one side.

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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